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Staff
Dr. Shurjo Sen is a program director in NHGRI's Division of Genome Sciences who manages a portfolio of grants focused upon genomic data sciences, and is particularly interested in transitioning genomics from a centralized data repository model to cloud-based collaborative science.
… transitioning genomics from a centralized data repository model to cloud-based collaborative science. Apart from … mice born to wild mice have natural microbiota and model human immune responses . Science 2019 Aug 2;365(6452) [ … transitioning genomics from a centralized data repository model to cloud-based collaborative science. … Shurjo Sen, …
Educational Resources
Metagenomics is the study of the structure and function of entire nucleotide sequences isolated and analyzed from all the organisms (typically microbes) in a bulk sample.
… nucleotide sequences isolated and analyzed from all the organisms (typically microbes) in a bulk sample. … … nucleotide sequences isolated and analyzed from all the organisms (typically microbes) in a bulk sample. Metagenomics … nucleotide sequences isolated and analyzed from all the organisms (typically microbes) in a bulk sample. … …
Genetic Disorders
Wilson disease is a rare genetic condition that causes a person's body to store too much of the mineral copper, leading to organ damage that may cause death.
Talking Glossary
CRISPR (short for “clustered regularly interspaced short palindromic repeats”) is a technology that research scientists use to selectively modify the DNA of living organisms.
… scientists use to selectively modify the DNA of living organisms. … CRISPR (short for “clustered regularly … scientists use to selectively modify the DNA of living organisms. CRISPR was adapted for use in the laboratory from … scientists use to selectively modify the DNA of living organisms. … Talking Glossary …
Research Funding
The NHGRI Ethical, Legal and Social Implications (ELSI) Research Program Abstracts and Activities Database organizes abstracts for all ELSI-related activities
Staff
Dr. Raman Sood is an associate investigator in the Translational and Functional Genomics Branch and director of the Zebrafish Core at the National Human Genome Research Institute. ​
… functional genomic analyses of genes using the zebrafish model. With expert advice from Drs. Paul Liu and Shawn … biology tools, genomic technologies and zebrafish as a model system. In the Translational and Functional Genomics … and disease pathophysiology. Zebrafish as a vertebrate model offers several advantages, such as external …
15 Ways Genomics Influences Our World
Genomics helps us understand evolution and protect our biological ecosystems.
… have been used to read the genomes of tens of thousands of organisms, some alive and some extinct, allowing us to … our genomes. Genomics helps us understand the biology of organisms across the world: why are some faster or smarter … human!). We have also had to change the placement of some organisms on the "Tree of Life" - like when we learned that  …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… behaviors. For example, "Methuselah" is a knockout mouse model noted for longevity, while "Frantic" is a model useful for studying anxiety disorders. … While knockout … with an artificial piece of DNA. … Knockout Mouse, Animal Model, Laboratory Experiment, DNA, Embryonic Stem Cells, …
Staff
Dr. Shawn Burgess is the deputy director of NHGRI's Intramural Research Program.
… directly tested. Because the genomes of the vertebrate model organisms mouse ( Mus musculus ) and zebrafish ( Danio rerio …
Educational Resources
Epigenetics is an emerging field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism.