Search Results
Educational Resources
A knockout typically refers to an organism that has been genetically engineered to lack one or more specific genes.
… genes from an organism. Scientists create knockout organisms to study the impact of removing a gene from an …
Educational Resources
Mendelian inheritance refers to certain patterns of how traits are passed from parents to offspring.
… to patterns of inheritance that are characteristic of organisms that reproduce sexually. … Mendelian Inheritance, …
Educational Resources
An organelle is a subcellular structure that has one or more specific jobs to perform in the cell, much like an organ does in the body.
Policy Issues
Federally-funded research with human participants must comply with regulations that protect the rights and welfare of the participants.
… and discoveries that could not be otherwise obtained using model organisms or other methods. All federally-funded research … of genetic markers for human diseases. While model organisms remain powerful research tools, working with …
About NHGRI
NHGRI is advancing human health and spurring innovation by building bridges between our research laboratories and the academic, non-profit and private sectors.
… to proceed pending final negotiation and review. A model agreement developed by the NCI is provided. … of intellectual property rights to the collaborator. A model agreement developed by the NCI is provided. Materials … of confidential research information. Several different model versions of CDA's developed by the NCI are provided. … …
Partner with NHGRI
NHGRI's technologies, inventions and discoveries are available for licensing.
… of Technology Transfer Abstract  … Mouse Models Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular … (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI) Murine Model of Niemann-Pick Disease Type C DHHS Reference No.: … Lead Inventor: William J. Pavan, Ph.D., (NHGRI) Mouse Model of Diamond-Blackfan Anemia DHHS Reference No.: …
Jobs at NHGRI
A postdoctoral training position is currently available in the Computational and Statistical Genomics Branch (CSGB) of the National Human Genome Research Institute (NHGRI).
… of high-quality whole-genome sequencing data from these organisms. The successful applicant will have the opportunity …
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… between humans and domestic dogs provides an emerging model of aging. … One of the most common misconceptions is … the results obtained with humans. Dogs are a useful model for such comparisons because much of their environment, …
Research at NHGRI
The Technology Transfer Office is responsible for transferring NHGRI technologies to the private sector and exchanging research materials with outside groups.
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… National Institutes of Health live nearly half a million organisms that breathe underwater, develop from an egg so … researchers, the reasons for using zebrafish as their model organism of choice are as varied as the diseases they … For Dr. Brooks' research program, using the zebrafish as a model is both practical and eye-opening."The zebrafish …