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Educational Resources
Epistasis is a circumstance where the expression of one gene is affected by the expression of one or more independently inherited genes.
… by the expression of one or more independently inherited genes. … Gene Expression, Gene Variation, DNA, Genes … Epistasis is a circumstance where the expression of … or suppressed) by the expression of one or more other genes. … Epistasis is a circumstance where the expression of …
News Release
NIH researchers have created a data resource show how differences in an individual's genome can affect gene activity and contribute to disease.
… in the DNA code - control how, when and how much genes are turned on and off in different tissues, and can … individuals in order to understand the causal effects of genes and variants, and which tissues contribute to … a kidney cell different from a liver cell is the set of genes that are turned on (expressed) and off over time and …
Educational Resources
In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene.
… passed on the gene. … Genetic Imprinting, DNA Sequence, Genes, Family Health History, Genealogy, Gene Expression … … genomic mutations that can affect the ability of inherited genes to be expressed, genomic imprinting does not affect the … egg or sperm formation. Epigenetic tags on imprinted genes usually stay in place for the life of the individual. … …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… , your stem cells are changed by altering part of your genes. Types of gene therapy include gene addition and gene … are present at the time of the gene therapy nor alter the genes that you pass on to your children. … Bone marrow … your stem cells are replaced with new stem cells that have genes that do not code for sickle cell disease. These new …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… four different chemicals, organized into 20,000 to 25,000 genes. For the instructions to be carried out, DNA must be … the world-the Mammalian Gene Collection initiative and the Mouse Transcriptome Project. The Mammalian Gene Collection … initiative built a free, public library of human, mouse, and rat mRNA sequences. The project was led by NHGRI …
News Release
NIH will award nearly $80 million to support the establishment of the Mendelian Genomics Research Consortium and the development of novel methods and approaches that help researchers identify the genetic causes of single-gene diseases.
… have been identifying about 300 Mendelian disease genes each year using a technique called whole-exome … sequencing has not been successful in identifying the genes responsible for many Mendelian diseases, requiring new … find innovative methods to increase the rate at which the genes responsible for all Mendelian diseases can be …
Educational Resources
A genotype is an individual's collection of genes.
… Genotype … A genotype is an individual's collection of genes. … Genotype, Genes, DNA Sequence, Phenotype … A genotype is a scoring of … phenotype. … A genotype is an individual's collection of genes. … Educational Resources …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… in health and disease. Genetics refers to the study of genes and the way that certain traits or conditions are … another. Genomics describes the study of all of a person's genes (the genome). … Genetics is a term that refers to the study of genes and their roles in inheritance - in other words, the …
News Release
NIH will award $38.5 million over five years to the Developmental Genotype-Tissue Expression (dGTEx) project, which aims to build a widely available resource of human developmental gene expression in a multitude of tissues for use in basic and clinical research.
… scientists needed to understand how differences in our genes directly affect the makeup and function of our bodies. … “We hope this project will lend more insight into how our genes are expressed at each stage in our lives.” Multiple … We hope this project will lend more insight into how our genes are expressed at each stage in our lives. “It’s tragic …