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The Genomics Landscape
In the November 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 25th anniversary of NHGRI's Intramural Research Program.
… Genome Gene Mutation Points to New Way to Fight Diabetes, Obesity, Heart Disease Study Identifies Gene that Makes …
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… HL 5,360 (41.9% female) Autism, appendicitis, childhood obesity Geisinger Health System 22,000; 99.4% EA 4,191 (47.5% female) AAA, extreme obesity and related conditions, remission of diabetes after …
News Release
Researchers show critical association between diabetes and previously unlinked ZRANB3 gene.
… and metabolic diseases; digestive diseases, nutrition, and obesity; and kidney, urologic, and hematologic diseases. For …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… of type 2 diabetes, Parkinson's disease, heart disorders, obesity, Crohn's disease and prostate cancer, as well as …
Fact Sheets
Epigenomics is a field in which researchers chart the locations and understand the functions of all the chemical tags that mark the genome.
… with poor muscle tone and constant hunger, leading to obesity; and Angelman syndrome, which leads to intellectual …
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… as a high proportion of AA with CVD risk factors such as obesity and hypertension that predispose to the eventual …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… include studying and modeling different kinds of cancer, obesity, heart disease, diabetes, arthritis, substance abuse, …
News Release
Researchers sequence the genomes of healthy participants, then analyze the data to find presumed, mutations that might lead to a genetic condition.
… and metabolic diseases; digestive diseases, nutrition and obesity; and kidney, urologic and hematologic diseases. …
News Release
Scientists from the 1000 Genomes Project Consortium has created the world's largest catalog of genomic differences among humans.
… from cognitive disabilities to susceptibilities to cancer, obesity, diabetes, heart disease and other disorders. …
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… Crohn’s disease, GERD, necrotizing enterocolitis (NEC)obesity, metabolic syndrome, type 1 and type 2 …