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An animal model is a non-human species used in medical research because it can mimic aspects of a disease found in humans.
… like humans in their anatomy, physiology or response to a pathogen that researchers can extrapolate the results of …
News Release
Researchers at NHGRI have discovered an immune mechanism in humans that perceives threats and was found only in plants.
… instead of immune molecules sensing and responding to a pathogen directly, which was thought to be the sole counter … molecules and white blood cells to annihilate the pathogen - a response, in some cases, that's orchestrated by … through a single mechanism, instead of developing pathogen-specific defenses, Dr. Chae explained. Studies like …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… that the dendritic cell undergoes when it encounters a pathogen, including the genes that are turned on and off, … white blood cell called a macrophage reacts to a bacterial pathogen, which can result in the activation of more than …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
Staff
Dr. Sean Conlan is an associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.​
… Holland SM. Adaptability and persistence of the emerging pathogen Bordetella petrii . PLoS One, 8(6): e65102. 2013 . [ …
Research Funding
The Knockout Mouse Phenotyping Project (KOMP2) collaborates with the International Mouse Phenotyping Consortium (IMPC) to knockout and characterize all protein-coding genes in the mouse genome.
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… function of pyrin in healthy individuals. In doing so, the pathogen suppresses the body's inflammatory response to the … increase patients' survival rate when infected by the pathogen. To test this hypothesis, the researchers …
15 Ways Genomics Influences Our World
Genomics is empowering farmers to improve the food supply.
Secondary Genomics Finding Service
Clinical Research Staff and Protocol Coordinators
Staff
Dr. Keith McKenney is a scientific review officer at the National Human Genome Research Institute (NHGRI).