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News Release
20 papers published online in 2014 highlight research on DNA biorepositories and electronic medical records to better understand the genomics of disease.
… The major goal of eMERGE is to better understand disease risk and susceptibility and, ultimately, improve patient … developing screening methods for individuals who are at risk for severe side effects from taking thiopurine drugs, … would like to be able to use this information to improve risk assessment and treatment for these and other disorders. …
15 Ways Genomics Influences Our World
Advances in genomics are helping you access information about your genome from your home.
Staff
Lindsey Criswell, who became the director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases in February, 2021 is also an associate investigator in NHGRI's Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch.
… Disease Genomics Branch. … Lindsey Criswell, genetic risk factors, autoimmune disease, rheumatoid arthritis (RA); …
Research Training
This program offers training in a combined program of maternal-fetal medicine and medical genetics.
… of genetic and metabolic disease on healthy and high risk pregnancies. The four year training program is open only … Genetic And Metabolic Disease, Healthy Pregnancies, High-risk Pregnancies, Obstetrics And Gynocology, Amniocentesis, …
Fact Sheet
Diversity among genomics research participants is essential for improving the health of everyone.
… all populations. … Every human has some baseline genetic risk of developing a given disease. Extensive research has … levels. This way, researchers can better define a person's risk of developing a specific disease and design a clinical … the Wellcome Trust and the African Academy of Sciences.  Polygenic Risk Score (PRS) Diversity Consortium (2021 - 2027) …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
… will be notified by mid-October 2023. All the best,  … Polygenic scoring accuracy varies across the genetic ancestry … the case that variants in many genes contribute to the risk of developing traits and diseases. Scientists and clinicians use tools called polygenic scores to calculate such a risk by combining information …
Research Funding
The E​MERGE Network develops, disseminates and applies approaches to research that combine biorepositories with electronic medical record systems.​
… and Missions  Working Group Co-Chairs Goals Comprehensive Risk Assessment and Return Gail Jarvik, Iftikhar Kullo, and … and Management Network aims to: calculate and validate polygenic risk scores (PRS) in diverse populations for 10 conditions, …
News Release
By considering mixed genetic lineages, NHGRI researchers demonstrated that previously inferred links between a genomic variant that helps digest lactose and traits such as a person’s height and cholesterol level may not be valid.
… are related to different traits helps researchers estimate polygenic risk scores and may give clues about a person’s ability to respond …
The Genomics Landscape
In the August 2019 edition of The Genomics Landscape, NHGRI Director Eric Green recognizes the recipients for the Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor given by the U.S. Government to outstanding scientists and engineers who are beginning their independent research careers.
… The meeting, entitled Genomic Medicine XII: Genomics and Risk Prediction , assessed the biomedical landscape related to polygenic risk scores and how it may be improved. It also aimed to identify …
The Genomics Landscape
In the January 5, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how artificial intelligence and machine learning are becoming omnipresent throughout NHGRI and in genomics.
… these metabolic changes can impact physical traits such as risk of disease or drug toxicity. In this paper (Surendren et … ML is being used for improving the methods for calculating polygenic risk scores , which reflect an individual's genetic risk for a …