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Educational Resources
A lymphocyte is a type of white blood cell that is part of the immune system.
… Lymphocyte … A lymphocyte is a type of white blood cell that is part of the immune system. … Lymphocytes, White Blood Cell, Immune System … A lymphocyte is a type of white … immune system. There are two main types of lymphocytes: B cells and T cells. The B cells produce antibodies that are …
News Release
A simple blood draw is replacing a giant needle to the belly for testing their fetuses for a range of genetic disorders.
… breathing a collective sigh of relief now that a simple blood draw is replacing a giant needle to the belly for … for a range of genetic disorders. This non-invasive blood test, combined with advances in genomic medicine, has … they view the related ethical issues." Through a simple blood test, physicians will soon be able to determine the …
Educational Resources
An antibody is a protein component of the immune system that circulates in the blood, recognizes foreign substances like bacteria and viruses, and neutralizes them.
… component of the immune system that circulates in the blood, recognizes foreign substances like bacteria and … and neutralizes them. … Immune System, Bacteria, Virus, Blood, Circulation, Disease, Antigen … An antibody is a … component of the immune system that circulates in the blood, recognizes foreign substances like bacteria and …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… Types of treatments A variety of approaches target the blood stem cells to reduce your symptoms of sickle cell disease. Gene … aim to decrease the amount of hemoglobin S in your red blood cells. If they successfully decrease the hemoglobin …
Talking Glossary
Cell-free DNA testing is a laboratory method that involves analyzing free (i.e., non-cellular) DNA contained within a biological sample, most often to look for genomic variants associated with a hereditary or genetic disorder.
Fact Sheet
Today, gene therapy for sickle cell disease is considered experimental and only available to you if you participate in a clinical trial.
… also be required to have: Certain screenings (e.g., MRI, blood tests). A genetic test to determine if there are … cell collection (~90 days) Gene therapy requires stem cells to be collected from your bone marrow or blood, taken to a lab for modification, then returned to you. …
News Release
NHGRI researchers have released new educational materials to help the sickle cell disease community learn about gene therapies for the disease.
… of Health, particularly the National Heart, Lung, and Blood Institute.” “Most importantly, the project included … name of the disease comes from the “sickle” shape of the red blood cells that form in patients with the disorder. Red blood …
Educational Resources
Sickle cell disease is a hereditary disease seen most often among people of African ancestry.
… as an autosomal recessive trait. The mutation causes the red blood cells to take on an unusual sickle shape. Individuals …
News Release
Researchers explored patients', parents' and physicians' perspectives on the use of CRISPR-Cas9 gene-editing to reverse sickle cell disease.
… community." In September, NIH's National Heart, Lung, and Blood Institute launched the Cure Sickle Cell Initiative to … and India, is caused by a single gene mutation that causes red blood cells to take on an unusual sickle shape. People affected by …
Clinical Research
The INSIGHTS study is exploring sickle cell disease in adults.
… cell disease. We will measure biomarkers for stress from blood and hair, and collect self-reported experiences with … and physical environment and current quality of life Blood sample will be collected to study your current health … about Sickle Cell Disease National Heart, Lung, and Blood Institute- Sickle Cell Disease Centers for Disease …