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News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… better understand what mutations - changes to the cancer cell's DNA - may lead to relapse. In recent research … A genome can be thought of as a huge DNA "book" in each cell that includes all of our genes (the chapters), and … significant differences between the genome of a healthy cell and that of a cancer cell. The analysis of the cancer …
Talking Glossary
Mosaicism refers to the presence of cells in a person that have a different genome from the body’s other cells.
… later in development. Mosaicism can affect any type of cell and does not always cause disease. … Mosaicism refers to …
News Release
A team from the NIH has surmounted a major obstacle to testing potential drug therapies for a rare, genetic condition called Gaucher disease.
… spleen, bone marrow and nervous system. The main type of cell that is affected by accumulated glucocerebroside is the macrophage, a type of white blood cell. Macrophages are cellular housekeepers that dispose of cell debris and pathogens. According to the study, …
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… Cellular Signatures (LINCS). Discovering such cell responses will improve scientists' understanding of cell pathways and aid in the development of new therapies for … second phase of LINCS is to optimize the combinations of cell types, perturbations and measurements of cellular …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
Talking Glossary of Genetic Terms
Race is a fluid concept used to group people according to various factors including, ancestral background and social identity.
… including, ancestral background and social identity. … Trait, Genetic Variation … Race is a social construct used to …
The Genomics Landscape
In the June 2020 edition of The Genomics Landscape, NHGRI Director Eric Green details NHGRI's new Diversity in Genomics Workforce Initiative.
… gene-editing therapy to cure an individual with sickle cell disease. This has been heralded as a landmark moment for … the use of gene editing for treating inherited diseases. Sickle cell disease is a group of disorders that affects …
News Release
By considering mixed genetic lineages, NHGRI researchers demonstrated that previously inferred links between a genomic variant that helps digest lactose and traits such as a person’s height and cholesterol level may not be valid.
Talking Glossary
Chromosomes are threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information from cell to cell.
… of DNA that serve to carry the genomic information from cell to cell. … Chromosomes are threadlike structures made of protein … of DNA that serve to carry the genomic information from cell to cell. In plants and animals (including humans), …
Talking Glossary
A gamete is a reproductive cell of an animal or plant.
… Gamete … A gamete is a reproductive cell of an animal or plant. … A gamete is a reproductive cell of an animal or plant. In animals, female gametes are … called sperm. Ova and sperm are haploid cells, with each cell carrying only one copy of each chromosome. During …