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News Release
NHGRI awards $6.7 million in new research grants to develop DNA sequencing technologies that are more sensitive, faster, cheaper and more accurate.
Media Availability
New research provides a better understanding of some of the genetic and cellular changes in pathways and processes involved in Autism Spectrum Disorder.
… off, and the formation of neural connections in the brain. Transcription. Instructions embedded in genes must be … or read, to build proteins, the workhorse of the cell. Transcription mistakes can affect a wide range of important …
Genomics Teaching Tool
An activity that demonstrates how DNA can be isolated from a strawberry using common household items.
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… year used LINCS data to identify the role of a critical transcription regulator, heat shock factor 1 (HSF1), in …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… that form a dimer for DNA binding and gene expression regulation, are frequent targets of such chromosome … Sood, has used zebrafish to study the roles of several transcription factor genes in hematopoiesis, such as runx1 , … Freedman M, Siciliano MJ, and Collins FS. Fusion between transcription factor CBFb/PEBP2b and a myosin heavy chain in …
Fact Sheet
Genomic research has been central to understanding and combating the SARS-CoV-2 (COVID-19) pandemic.
… RNA to double-stranded DNA in a process called reverse transcription. The two DNA template strands are then …
Research at NHGRI
NHGRI researchers develop freely available software and analysis tools to help researchers around the world analyze and explore their genomic data.
Staff
Dr. Marjan Huizing is a staff scientist in the Medical Genetics Branch at the National Human Genome Research Institute.
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Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… ZFN must be engineered for each new target DNA sequence. Transcription activator-like effector nucleases (TALENs) In 2009, a new class of proteins called Transcription Activator-Like Effector Nucleases (TALENs) …  arrived to the genome editing scene. Similar to ZFNs, transcription activator-like effector nucleases (TALENs) are …
FAQ
Frequently asked questions related to the Informational Session on the Renewed ELSI Funding Opportunities: R01 (PAR-23-293), R21 (PAR-23-294), and R03 (PAR-23-295).