Search Results
Talking Glossary of Genetic Terms
Race is a fluid concept used to group people according to various factors including, ancestral background and social identity.
Clinical Research
The Attention Deficit/Hyperactivity Disorder (ADHD) Genetic Research Study explores the genetic factors contributing to ADHD to improve treatment in the future.
News Release
CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and triglycerides.
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… are driven primarily by mutations in one of two cancer-associated genes: BRAF (and a particular mutation, V600E ) or … types, particularly in signaling pathways that promote tumor development and growth. The researchers developed a … to characterize tumors and determine both the pathway a tumor uses to send signals and its relative aggressiveness. …
Educational Resources
Genetic epidemiology is a relatively new medical discipline that seeks to understand how genetic factors interact with the environment in the context of disease in populations.
Genetic Disorders
Hemophilia is a bleeding disorder that slows down the blood clotting process.
… who have hemophilia A have low levels of a blood clotting factor called factor eight (FVIII). People who have hemophilia B have low levels of factor nine (FIX). The two types of hemophilia are caused by …
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… is important to the onset of symptoms and complications associated with SCD. Dr. Koehly's team is also reviewing …
Research Funding
The developmental Genotype-Tissue Expression initiative's goal is to catalog and analyze transcriptional profiles from a wide variety of tissues from the pediatric period, including neonates through adolescents, in a post-mortem setting.
… dGTEx Project will establish a database, data portal, and associated tissue bank with data and samples from a minimum … (NHP dGTEx) Project will establish a resource database and associated tissue bank with data and samples from old world … dGTEx initiative is to establish a resource database and associated tissue bank to study gene expression patterns in …