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News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… to the other during sexual contact, without the help of a virus or bacterium. … By comparing the genomes of 186 healthy …
News Release
It’s teatime and doctors, researchers and patients are at the table. They celebrate a decade of work and launch the first in-human gene therapy trial for children with a rare and devastating disease, GM1 gangliosidosis.
… in creating the gene therapy vector -- an unwitting virus that would deliver functioning copies of the defective … infections are generally viewed negatively. Take the flu virus, for example: It moves into the respiratory tract, … inserts genetic information, causing fever and aches.  A virus delivers its genetic information into the cell. Credit: …
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… clinical trials aims to combat human immunodeficiency virus (or HIV) infection. HIV enters human white blood cells … to combat HIV immediately found that on its own, the virus developed separate new mutations that allowed it to … escape the CRISPR edits.  These new mutations allowed the virus to start replicating again. As scientists working on …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… on the brain. To do this, they used a non-disease-causing virus called the adeno-associated virus serotype 9 (AAV9) to transfer functioning NPC1 to the …
Clinical Research
A study to learn more about the role of viral infection and biomarkers of immunity in mitochondrial disease, utilizing new technology with Neoteryxâ„¢ fingerstick at-home sampling.
… for antibodies that indicate exposure to SARS-CoV-2 (the virus that causes COVID-19) and other viruses. People often …
News Release
NHGRI will highlight rare disease research that benefits affected patients and provides insights into more common disorders on Rare Disease Day.
Staff
Dr. Bettie Graham was the division director for NHGRI's Division of Extramural Operations.
… map of the origin of defective DNA in Herpes Simplex virus Type 1 DNA. J. Virol , 25: 878 887, 1978. [ PubMed ] …
Event
On January 11, 2021, NHGRI and The George Washington University organized an interactive webinar.
Educational Resources
A lymphocyte is a type of white blood cell that is part of the immune system.