NHGRI logo
Program Director

Division of Genomic Medicine

Education

Ph.D. Duke University, 2008

Biography

Dr. Wise is a program director in the Division of Genomic Medicine at the National Human Genome Research Institute (NHGRI). She received her Ph.D. in genetics and genomics from Duke University and joined NHGRI in 2010. At NHGRI she serves as project officer for programs advancing the application of genomics to medical science and clinical care with a focus on perinatal sequencing, undiagnosed and rare disease genomic medicine, and sex chromosome analysis and association methods. Dr. Wise serves as co-coordinator and program director for the NIH Common Fund's Undiagnosed Diseases Network, which aims to form a sustainable national resource to diagnose both rare and previously undiagnosed diseases through team science. She is also a project scientist for the Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT) program, which aims to explore the potential implications, challenges and opportunities associated with the possible use of genomic sequence information in the newborn period. Her other research interests include gene-environment interactions in complex disease, pharmaco/toxicogenomics, and ethical, legal, and social issues related to the use of genetic information.

Publications

Ramoni RB, Mulvihill JJ, Adams DR, Allard P, Ashley EA, Bernstein JA, Gahl WA, Hamid R, Loscalzo J, McCray AT, Shashi V, Tifft CJ; Undiagnosed Diseases Network., Wise AL. The Undiagnosed Diseases Network: accelerating discovery about health and disease. Am J Hum Genet, 100(2):185-192. 2017. [PubMed]

Berg JS, Agrawal PB, Bailey DB Jr, Beggs AH, Brenner SE, Brower AM, Cakici JA, Ceyhan-Birsoy O, Chan K, Chen F, Currier RJ, Dukhovny D, Green RC, Harris-Wai J, Holm IA, Iglesias B, Joseph G, Kingsmore SF, Koenig BA, Kwok PY, Lantos J, Leeder SJ, Lewis MA, McGuire AL, Milko LV, Mooney SD, Parad RB, Pereira S, Petrikin J, Powell BC, Powell CM, Puck JM, Rehm HL, Risch N, Roche M, Shieh JT, Veeraraghavan N, Watson MS, Willig L, Yu TW, Urv T, Wise AL. Newborn sequencing in genomic medicine and public health. Pediatrics, 139(2). 2017. [PubMed]

Wise AL, Gyi L, Manolio TA. eXclusion: toward integrating the X chromosome in genome-wide association analyses. American Journal of Human Genetics. 92(5):643-7. 2013. [PubMed]

Last updated: September 23, 2018