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2013

May 2013

May 22, 2013: NIH researchers conduct first genomic survey of human skin fungal diversity
In the first study of human fungal skin diversity, National Institutes of Health researchers sequenced the DNA of fungi at skin sites of healthy adults to define the normal populations across the skin and to provide a framework for investigating fungal skin conditions. The study appears in the May 22, 2013 early online issue of Nature.

May 1, 2013: TCGA researchers identify potential drug targets, markers for leukemia risk
Investigators for The Cancer Genome Atlas (TCGA) Research Network have detailed and broadly classified the genomic alterations that frequently underlie the development of acute myeloid leukemia (AML), a deadly cancer of the blood and bone marrow. Their work paints a picture of a cancer marked by relatively few mutations compared to other types of cancer occurring in adults. The findings - which appeared online May 1, 2013 - in the New England Journal of Medicine set the stage for identifying potential new drug targets and treatment strategies for AML. They may also offer better guidance for predicting the severity of disease for individual patients.


May 1, 2013: Study establishes basis for genomic classification of endometrial cancers
A comprehensive genomic analysis of nearly 400 endometrial tumors suggests that certain molecular characteristics - such as the frequency of mutations - could complement current pathology methods and help distinguish between principal types of endometrial tumors, as well as provide insights into potential treatment strategies. The findings represent the most comprehensive characterization of the molecular alterations in endometrial cancers available to date. They were published May 2, 2013, in the journal Nature. TCGA is funded and managed by the National Cancer Institute and the National Human Genome Research Institute, both part of the National Institutes of Health.
 

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April 2013

April 12, 2013: NHGRI celebrates 10^th anniversary of the Human Genome Project
Like the Apollo program's single goal of landing a man on the moon and returning him safely, the Human Genome Project (HGP) had the single goal of deciphering the exact order of the 3 billion genetic letters encoding the information for producing a person. Since its completion on April 14, 2003, the National Human Genome Research Institute (NHGRI), one of the 27 institutes and centers at the National Institutes of Health, and the field of genomics have marched past numerous important milestones on the path to translating genomic findings into medical advances.

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January 2013

January 6, 2013: Genetic mystery of Behcet's disease unfolds along the ancient Silk Road
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics.

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Last Updated: May 22, 2013