Gerard Bouffard, Ph.D.

Associate Investigator, Genome Technology Branch
Director, Bioinformatics Group, NIH Intramural Sequencing Center [nisc.nih.gov]

Selected Publications

Bouffard G.G., Rudd K.E., Adhya S.L. Dependence of lactose metabolism upon mutarotase encoded in the gal operon in Escherichia coli. J Mol Biol, 244(3):269-78. 1994. [PubMed]

Bouffard G.G., Idol J.I., Braden V.V., Iyer L.M., Cunningham A.F., Weintraub L.A., Touchman J.W., Mohr-Tidwell R.M., Peluso D.C., Fulton R.S., Ueltzen M.S., Weissenbach J., Magness C.L., Green E.D. A physical map of human chromosome 7: an integrated YAC contig map with average STS spacing of 79 kb. Genome Res, 7:673-692. 1997. [PubMed]

Gubin A.N., Njoroge J.M., Bouffard G.G., Miller J.L. Gene expression in proliferating human erythroid cells. Genomics, 59(2):168-77. 1999. [PubMed]

Andrews J., Bouffard G.G., Cheadle C., Lu J., Becker K.G., Oliver B.. Gene discovery using computational and microarray analysis of transcription in the Drosophila melanogaster testis. Genome Res, (12):2030-43. 2000. [PubMed]

Shevchenko Y, Bouffard G.G., Butterfield Y.S., Blakesley R.W., Hartley J.L., Young A.C., Marra M.A., Jones S.J., Touchman J.W., Green E.D. Systematic sequencing of cDNA clones using the transposon Tn5. Nucleic Acids Res, 30(11):2469-77. 2002. [PubMed]

Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A. Mammalian Gene Collection Program Team. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A, 99(26):16899-903. 2002 [PubMed]

Thomas J.W., Touchman J.W., Blakesley R.W., Bouffard G.G., Beckstrom-Sternberg S.M., Margulies E.H., Blanchette M., Siepel A.C., Thomas P.J., McDowell J.C., Maskeri B., Hansen N.F., Schwartz M.S., Weber R.J., Kent W.J., Karolchik D., Bruen T.C., Bevan R., Cutler D.J., Schwartz S., Elnitski L., Idol J.R., Prasad A.B., Lee-Lin S.Q., Maduro V.V., Summers T.J., Portnoy M.E., Dietrich N.L., Akhter N., Ayele K., Benjamin B., Cariaga K., Brinkley C.P., Brooks S.Y., Granite S., Guan X., Gupta J., Haghighi P., Ho S.L., Huang M.C., Karlins E., Laric P.L., Legaspi R., Lim M.J., Maduro Q.L., Masiello C.A., Mastrian S.D., McCloskey J.C., Pearson R., Stantripop S., Tiongson E.E., Tran J.T., Tsurgeon C., Vogt J.L., Walker M.A., Wetherby K.D., Wiggins L.S., Young A.C., Zhang L.H., Osoegawa K., Zhu B., Zhao B., Shu C.L., De Jong P.J., Lawrence C.E., Smit A.F., Chakravarti A., Haussler D., Green P., Miller W., Green E.D. Comparative analyses of multi-species sequences from targeted genomic regions. Nature, 424(6950):788-93. 2003. [PubMed]

Blakesley R.W., Hansen N.F., Mullikin J.C., Thomas P.J., McDowell J.C., Maskeri B, Young A.C., Benjamin B., Brooks S.Y., Coleman B.I., Gupta J., Ho S.L., Karlins E.M., Maduro Q.L., Stantripop S., Tsurgeon C., Vogt J.L., Walker M.A., Masiello C.A., Guan X., Bouffard G.G., Green E.D. NISC Comparative Sequencing Program. An intermediate grade of finished genomic sequence suitable for comparative analyses. Genome Res 14:2235-2244. 2004.[PubMed]

Grice EA, Kong HH, Renaud G, Young AC; NISC Comparative Sequencing Program, Bouffard GG, Blakesley RW, Wolfsberg TG, Turner ML, Segre JA. A diversity profile of the human skin microbiota. Genome Res, May 23, 2008. [PubMed]

Grice EA, Kong HH, Renaud G, Young AC, NISC Comparative Sequencing Program, Bouffard GG, Blakesley RW, Wolfsberg TG, Turner ML, Segre JA. A diversity profile of the human skin microbiota. Genome Res, 18:1043-1050. 2008. [PubMed]

Grice EA, Kong HH, Conlan, S, Deming, CB, Davis, J, Young AC, NISC Comparative Sequencing Program, Bouffard GG, Blakesley RW, Segre JA. Topographical and temporal diversity of the human skin microbiome. Science, 324:1190-1192. 2009. [PubMed]

Biesecker LG, Mullikin JC, Facio FM, Turner C, Cherukuri PF, Blakesley RW, Bouffard GG, Chines PS, Cruz P, Green ED. The ClinSeq project: piloting large-scale genome sequencing for research in genomic medicine. Genome Res, 19:1665-1674. 2009. [PubMed]

MGC Project Team, Temple G, Gerhard DS, Rasooly R, Feingold EA, Good PJ, Robinson C, Mandich A, Bouffard GG, Wiemann S. The completion of the Mammalian Gene Collection (MGC). Genome Res , 19:2324-2333. 2009. [PubMed]

Blakesley RW, Hansen NF, Gupta J, McDowell JC, Maskeri B, Barnabas BB, Brooks SY, Coleman H, Bouffard GG, Green ED. Effort required to finish shotgun-generated genome sequences differs significantly among vertebrates. BMC Genomics, 11:21. 2010. [PubMed]

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Last Reviewed: January 30, 2013