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Technologies Available for Licensing

Genetic Technologies

  • N-Acetyl Mannosamine as a Therapeutic Agent
    DHHS Reference No. E-217- 2007/0-US-01
    Patent Status: U.S. Provisional Application No. 60/932,451 filed 31 May 2007
    Marjan Huizing, et al. (NHGRI)
    Federal Register Description

  • Substituted 3,6-diphenyl-7H-[1,2,4] triazolo[3,4-b] [1,3,4] Thiadiazines as Potent Inhibitors of PDE4A, PDE4B, and PDE4D
    DHHS Reference No. E0552008/ 0US01
    Patent Status: U.S. Provisional Application No. 61/020,079 filed 09 Jan 2008
    Craig J. Thomas, et al. (NHGRI)
    Federal Register Description

  • Methods and Materials for Identifying Polymorphic Variants, Diagnosing Susceptibilities, and Treating Disease
    DHHS Reference No. E-149-2005/0-PCT-01
    Patent Status: International Application No. PCT/US2005/21288 Filed: June 16, 2005
    Published as: WO 2007/001259 on Jan. 4, 2007
    Lawrence C. Brody, et al. (NHGRI)
    Federal Register Description

  • Viral Entry or Replication Inhibitors
    DHHS Reference No. E-151-2006/ 0-US-01
    U.S. Provisional Application No. 60/786,245 Filed: March 29, 2006
    PCT Application No. PCT/ US2007/007711 Filed: March 29, 2007
    DHHS Reference No. E-151-2006/1-PCT-01
    Julie Readinger, et al. (NHGRI)
    Federal Register Description

  • Latrophilin 3, a Gene Involved in Attention Deficit Hyperactivity Disorders
    U.S. Provisional Application No. 60/850,972 Filed: Oct. 11, 2006
    DHHS Reference No. E-312-2006/ 0-US-01
    Maximillian Muenke (NHGRI), Mauricio Arcos-Burgos (NHGRI), and F. Xavier Castellanos (NIMH)
    Federal Register Description

  • Identification of Molecular Markers for Endometriosis in Blood Lymphocytes Using DNA Microarrays
    DHHS Reference No. E-068-2005/0-US-01
    U.S. Provisional Application Filed: Feb. 18, 2005
    Idhaliz Flores (NHGRI), et al.
    Federal Register Description


  • Rapid Integration Site Mapping
    E-027-2004/0
    May 10, 2004
    Shawn Burgess
    Federal Register Despcription

  • Neural Crest-Melanocyte cDNA Based Microarray Analysis for Human Skin Pigmentation Research
    E-014-2002/0
    December 11, 2001
    William Pavan & Stacie K. Loftus (NHGRI)
    Federal Register Description

  • Quantifying Gene Relatedness via Nonlinear Prediction of Gene Expression Levels
    E-059-99/0
    December 26, 2000
    Dougherty et al.
    Federal Register Description

  • Tissue Microarrays for Rapid Molecular Profiling
    E-002-98/0, E-273-99/0, E-272-99/0, E-007-99/0, E-274-99/0
    October 25, 2000
    Kallionemi et al.
    Federal Register Description

Gene-Based Diagnostics

  • Genetic Markers for Body Size in Dogs
    U.S. Provisional Application No. 60/856,411 Filed: Nov. 2, 2006
    DHHS Reference No. E-009-2007/0-US-01
    Elaine A. Ostrander and Nathaniel B. Sutter (NHGRI)
    Federal Register Description

  • Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis
    DHHS Reference No. E-055-2005/0-US-01
    U.S. Provisional Application No. 60/648,307 Filed: Jan. 28, 2005
    Francis Collins (NHGRI) et al
    Federal Register Description

  • Methods for Analyzing High Dimensional Data for Classifying, Diagnosing, Prognosticating, and/or Predicting Diseases and Other Biological States
    DHHS Reference No. E-324-2001/0-US-01
    U.S. Patent Application No. 10/133,937 Filed: April 25, 2002
    Javed Khan and Paul S. Meltzer (NHGRI), et al.
    Federal Register Description

  • LMNA Gene and Its Involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and Arteriosclerosis
    E-020-2003/0-US-01 and E-131-2003/0-US-01
    August 26, 2003
    B. Maria H. Eriksson and Francis S. Collins (NHGRI)
    Federal Register Description
    News Release

  • Human Pendred Syndrome Gene
    E-004-98/0

  • Genes for Niemann-Pick Type C disorder
    E-122-97/0
    July 1997
    News Release

  • Gene Mutation for Parkinson's Disease
    E-190-97/0
    June 1997
    News Release

  • Gene for Multiple Endocrine Neoplasia Type 1 (MEN1)
    E-094-97/0
    April 1997
    News Release

  • Methods for Detecting Cervical Cancer
    E-012-97/0

Gene Therapy

  • Method for High-Level Globin Gene Expression
    E-291-97/0

  • Transgenomic Viruses
    E-011-97/0

  • Method for Producing Retrovirus RNA-Packaging Cassettes Amplified in Cytoplasm by Autocatalytic Togavirus Vectors
    E-135-96/0

Cancer Genetics

  • Cancer Genetics Monoclonal Antibody to the Protein NCOA6 (Also Called ASC-2, AIB-3)
    DHHS Reference No. E-168-2005/0- Research Tool
    Paul S. Meltzer (NHGRI)
    Federal Register Description


  • Methods for Detecting Cancer Cells
    E-211-1998/ 0-US-01
    December 9, 2003
    Thomas Ried
    Federal Register Description


  • Use of Interferon-Inducible 2',5'-Oligoadenylate-Dependent RNase in the Diagnosis, Prognosis and Treatment of Prostate Cancer
    E-196-01/1
    November 8, 2002
    Carpten, et al
    Federal Register Description

  • AIB1, A Novel Steroid Receptor Co-Activator Amplified in Human Breast Cancer
    E-018-97/0
    August 1997
    News Release

  • Gene for Multiple Endocrine Neoplasia Type 1 (MEN1)
    E-094-97/0
    April 1997
    News Release

  • Methods for Detecting Cervical Cancer
    E-012-97/0

Transgenics

  • SAP/SH2D1A Knockout Mice: A Model for X-linked Lymphoproliferative Disease
    E-343-2003/0
    February 24, 2004
    Pamela L. Schwartzberg (NHGRI)
    Federal Register Description

  • Tec Kinase Deficient Mice
    E-178-2003/0 and E-178-2003/1
    December 9, 2003
    Pamela L. Schwartzberg (NHGRI)
    Federal Register Description


  • Mouse Model of Multiple Endocrine Neoplasia Type I (MEN1)
    E-243-01/0
    August 14, 2001
    Crabtree & Collins
    Federal Register Description

  • Advanced Mouse Model for Huntington's Disease
    E-101-98/0
    October 1998
    News Release

  • Dvl-1-Deficient Mice for Investigating Psychiatric Disorders and Screening Behavior-Modifying Therapeutics
    E-100-97/0
    September 1997
    News Release

Current and Past Licensees of NHGRI Technologies

For information on licensing technologies, contact:

Claire T. Driscoll
Director, Technology Transfer Office
E-mail: cdriscol@mail.nih.gov

Felicia R. Bass
Technology Transfer Specialist
E-mail: fbass@mail.nih.gov

Address

Technology Transfer Office
Office of the Scientific Director
National Human Genome Research Institute
National Institutes of Health
5625 Fishers Lane, Room 5N-01/L/K, MSC 9400
Bethesda, MD 20892-9400

Phone: (301) 402-2537
Fax: (301) 402-9722

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Last Reviewed: June 1, 2009