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Researchers working at an NHGRI-supported large-scale sequencing center. Courtesy: The Broad Institute of MIT and Harvard

NIH-funded study uncovers range of molecular alterations in head and neck cancers, new potential drug targets

Read more Bethesda, Md., Tues., Jan. 28, 2015 - Investigators with The Cancer Genome Atlas (TCGA) Research Network have discovered genomic differences - with potentially important clinical implications - in head and neck cancers caused by infection with the human papillomavirus (HPV). HPV is the most common sexually transmitted virus in the United States, and the number of HPV-related head and neck cancers has been growing. Almost every sexually active person will acquire HPV at some point in their lives, according to the Centers for Disease Control and Prevention. Read more

NIH grants aim to decipher the language of gene regulation

Read moreBethesda, Md., Jan. 5, 2014 - The National Institutes of Health has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off. These awards emanate from the recently launched Genomics of Gene Regulation (GGR) program of the National Human Genome Research Institute (NHGRI), part of NIH. Read more


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Featured Grants

  • Interpreting Variation in Human Non-Coding Genomic Regions Using Computational Approaches and Experimental Assessment (R01)
    RFA-HG-13-013 []
    Application Receipt Date(s): January 21, 2014 and January 21, 2015
    Expiration Date: January 22, 2015


Convergent evolution of the genomes of marine animals

cover imageIn a recent paper in Nature Genetics, NHGRI funded researchers compared genomes of whales, dolphins, manatees and walruses to those of their closest land relatives (cow, dog and elephant). They found similar kinds of molecular changes throughout the marine genomes as the animals adapted to sea life. Surprisingly, they found the same kinds of genetic changes existed in land animals, suggesting that evolution likely makes use of a variety of pathways to drive adaptation. Read the paper: Convergent evolution of the genomes of marine animals. Nature Genetics, January 26, 2015.

Grant Writing: Advice from an NHGRI Pro

Bettie Graham, Ph.D.The National Human Genome Research Institute wants to help you write successful grant applications with tips to guide you through the process from Bettie Graham, Ph.D., a pro in grants administration for more than 30 years. (Read more)


Last Updated: January 28, 2015