Journal Articles by NHGRI Researchers and Staff

Recent Articles from NHGRI Archive: 2002-2011

2002

Andy Baxevanis, Ph.D.
Director, Computational Genomics Program. Deputy Director, Division of Intramural Research.

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2003

Francis S. Collins, M.D., Ph.D.
Former Director, NHGRI

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2004

Christopher P. Austin, M.D.
Adjunct Investigator, Genetics and Molecular Biology Branch, NHGRI
Francis S. Collins, M.D., Ph.D.
Former Director, NHGRI

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2005

Vence Bonham, J.D.
Senior Advisor to the Director on Societal Implications of Genomics
Francis S. Collins, M.D., Ph.D.
Former Director, NHGRI

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2006

Francis S. Collins, M.D., Ph.D.
Former Director, NHGRI
  • June 5, 2006: Human Genome Collection
    Nature presents the complete and comprehensive DNA sequence of the human genome as a freely available resource, plus new commentary by NHGRI Director Francis S. Collins, past Department of Energy Director Ari Patrinos and former director of the Sanger Centre John Sulston, among others.
     
Jean Jenkins, R.N., Ph.D., F.A.A.N.
Senior Clinical Advisor to the Director, NHGRI
  • May 15, 2006: Genetics and Genomics in Nursing
    NHGRI's Dr. Jean Jenkins edits a 15-article series on genetics and genomics in nursing for The Journal of Nursing Scholarship.

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2007

Francis S. Collins, M.D., Ph.D.
Former Director, NHGRI
  • March 2007: Mapping the Cancer Genome
    In the March issue of Scientific American, Former NHGRI Director Francis S. Collins and Deputy Director for Advanced Technologies and Strategic Partnerships of the National Cancer Institute Anna D. Barker find that pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies.
     
Alan Guttmacher, M.D., Ph.D.
Former NHGRI Deputy Director
  • January 29, 2007: Educating health-care professionals about genetics and genomics PDF icon
    NHGRI Acting Director and NHGRI Deputy Director Dr. Allen Guttmacher, et al, find that although genetics and genomics have transformed biomedical research, advances in the genomic literacy of healthcare providers is required to have an effect on clinical practice that is comparable to the impact on research. A Perspectives piece for Nature Reviews/Genetics.

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2008

Francis S. Collins, M.D., Ph.D.
Former Director, NHGRI
  • March 2008: The Genome Gets Personal - Almost PDF icon
    There are many rapid advances in personalized medicine to celebrate. But if the goal is to take full advantage of these discoveries, it is far too early to declare victory. A great deal of complex, groundbreaking, and multidisciplinary research is still needed before personal genomics reaches the mainstream of medicine.
     
W. Greg Feero, M.D., Ph.D.
Former Chief, Genomics Healthcare Branch, NHGRI
  • March 2008: The Genome Gets Personal - Almost PDF icon
    There are many rapid advances in personalized medicine to celebrate. But if the goal is to take full advantage of these discoveries, it is far too early to declare victory. A great deal of complex, groundbreaking, and multidisciplinary research is still needed before personal genomics reaches the mainstream of medicine.
Phyllis Frosst, Ph.D.
Former Head, Policy and Program Analysis Branch, NHGRI
  • February 19, 2008: Doing the Things that Interest You PDF icon
    In ASBMB Today, Dr. Frosst discusses her career as a Senior Science Policy Analyst for the National Human Genome Research Institute. ASBMB Today is a publication of the American Society of Biochemistry and Molecular Biology
Alan Guttmacher, M.D., Ph.D.
Former NHGRI Acting Director and Former NHGRI Deputy Director
  • March 2008: The Genome Gets Personal - Almost PDF icon
    There are many rapid advances in personalized medicine to celebrate. But if the goal is to take full advantage of these discoveries, it is far too early to declare victory. A great deal of complex, groundbreaking, and multidisciplinary research is still needed before personal genomics reaches the mainstream of medicine.
     
  • March 2008: Key Internet Genetics Resources for the Clinician [jama.ama-assn.org]
    As genomic information and genetic tests become more integrated into medical care, physicians need to know how to access genetic information and resources for their patients. Key Internet Genetics Resources for the Clinician can be used to find information about genetic factors in health and in specific diseases, supportive resources for patients, family history tools, genetic testing, state laws on use of genetic information for insurance and employment, and directories of genetics clinics and genetics professionals.
     
Teri Manolio, M.D., Ph.D.
Director, NHGRI Office of Population Genomics
  • March 2008: How to Interpret a Genome-Wide Association Study [jama.ama-assn.org]
    GWA studies are many steps removed from actual clinical use, and specific applications of GWA findings in prevention and treatment are actively being pursued. These studies mainly represent a valuable discovery tool for examining genomic function and clarifying pathophysiologic mechanisms. This article describes the design, interpretation, application, and limitations of GWA studies for clinicians and scientists for whom this evolving science may have great relevance.
Jeff Schloss, Ph.D.
Chief, Genome Technology Progam, NHGRI
  • October 2008: How to get genomes at one ten-thousandth the costPDF file
    The NHGRI's Advanced DNA Sequencing Technology program is spearheading the development of platforms that will bring routine whole-genome sequencing closer to reality. A commentary by Jeff Schloss, Ph.D.Chief, Genome Technology Program
     
  • October 2008: The potential and challenges of nanopore sequencing PDF file
    A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore. By Jeff Schloss, Ph.D., et al

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2009

Fabio Candotti, M.D.
Senior Investigator, NHGRI
  • January 29, 2009: Gene Therapy Fulfilling Its Promise [nejm.org]
    NHGRI Senior Investigator Fabio Candotti, M.D., of the Genetics and Molecular Biology Branch, and co-author Donald B. Kohn, M.D., Keck School of Medicine, University of Southern California, comment on prospects for continuing advancement of gene therapy for treatment of genetic diseases in light of the outcome of gene therapy for severe combined immunodeficiency disease, or SCID, due to deficiency of the enzyme adenosine deaminase (ADA), reported in recent trials.
     
    • Dr. Candotti's and Dr. Kohn's comments were based on the NEJM article: Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency [Abstract]
Yingzi Yang, Ph.D.
Senior Investigator, NHGRI

January 13. 2009: Growth and Patterning in the Limb: Signaling Gradients Make the Decision [stke.sciencemag.org]
Alterations in the duration and range of the signaling gradients may underlie many of the morphological differences in the evolution of vertebrate limbs.


Jeff Schloss, Ph.D.
Lead, Genome Technology Program, NHGRI
  • November 2009: The challenges of sequencing by synthesisPDF file
    Today's high throughput, low cost sequencing systems have brought revolutionary advances to our ability to sequence increasing numbers of genomes for research and early clinical applications. Further improvements could further reduce cost and improve genome quality.

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2010

Teri Manolio, M.D., Ph.D.
Director, Office of Population Genomics, NHGRI
  • November 26, 2010: Enhancing the Feasibility of Large Cohort Studies [jama.ama-assn.org]
    A recent Journal of the American Medical Association article, Enhancing the Feasibility of Large Cohort Studies by NHGRI's Teri Manolio, M.D., Ph.D. and Dr. Rory Collins at the University of Oxford, UK, focuses on the need for large cohorts to reliably assess genetic and environmental factors.

New England Journal of Medicine Series on Genomic Medicine
  • Greg Feero, M.D., Ph.D., Genomic Healthcare Branch
  • Teri Manolio, M.D., Ph.D. Office of Population Genomics
  • Charles Rotimi, Ph.D. Inherited Disease Reseaerch Branch
  • November 1, 2010: New England Journal of Medicine Series on Genomic Medicine
    The publication of the draft sequence of the human genome in 2000 heralded the promise of incorporating genomic knowledge into patient care. Ten years later, a new series of articles, beginning with the May 27, 2010 issue of the New England Journal of Medicine, is taking a comprehensive look at what has been accomplished in the quest to screen, prevent and treat disease in the new world of genomic medicine.
Elaine Ostrander, Ph.D.
Senior Investigator, NHGRI
  • March 1, 2010: Canine Morphology: Hunting for Genes and Tracking Mutations [plosbiology.org]
    An essay by NHGRI Senior Investigator Elaine Ostrander, Ph.D., and co-author Abigail Shearin, a University of Pennsylvania veterinary student pursuing research in the Ostrander Lab, explore why domestic dogs vary so much in size and shape, as well as coat texture, color and patterning. The essay highlights the unique features of dog populations that offer advantages for genetic studies

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2011

W. Gregory Feero, M.D., Ph.D and Eric D. Green, M.D., Ph.D., Director, NHGRI
  • September 7, 2011: Genomics Education for Health Care Professionals in the 21st Century [JAMA]
    In a recent Journal of the American Medical Association article, Genomics Education for Health Care Professionals in the 21st Century, W. Gregory Feero, M.D., Ph.D. and Eric D. Green, M.D., Ph.D., focus on how recent genomic discoveries have brought about far-reaching advances in understanding the molecular basis of human health and disease. NHGRI's vision for the future of genomics research suggests more discoveries are likely to occur over the next few decades.
  • Jean Jenkins, Ph.D., R.N., F.A.A.N.
    Office of Policy, Communications and Education, NHGRI
  • March 7, 2011: Genetics/Genomics and Nursing Education [wiley.com]
    To support genetic and genomic training in healthcare professional education programs, Jean Jenkins, Ph.D., R.N., F.A.A.N., National Human Genome Research Institute (NHGRI), and Kathleen Calzone, M.S.N., R.N., A.P.N.G., F.A.A.N., National Cancer Institute (NCI), have coordinated a series of articles that highlight the importance of genetics and genomics for nurse educators and nursing education worldwide. Genetics/Genomics and Nursing Education, will appear free in the Journal of Nursing Scholarship throughout 2011.

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Last Reviewed: January 13, 2015