2012 Release: NIH Human Microbiome Project defines normal bacterial makeup of the body

Human Microbiome Project (HMP) Telebriefing Resources

HMP logoThe Human Microbiome Project (HMP) is an interdisciplinary research effort at the National Institutes of Health that aims to characterize the microbial communities found at several different sites on the human body, including nasal passages, oral cavities, skin, gastrointestinal tract, and the urogenital tract, and analyze the role of these microbes in human health and disease.

In a series of coordinated scientific reports published on June 14, 2012, in Nature and several journals in the Public Library of Science (PLoS), some 200 members of the Human Microbiome Project (HMP) Consortium from nearly 80 universities and scientific institutions report on five years of research.

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Human Microbiome Project (HMP) Published Papers

A series of coordinated scientific reports published on June 13, 2012, in Nature and several journals in the Public Library of Science (PLOS)

Nature Papers
Public Library of Science (PLOS) Papers

Human Microbiome Project (HMP) Resources

  • Human Microbiome Project
    On the National Institutes of Health Common Fund website
  • Human Microbiome Project: The Broad Institute
    The Broad Institute's goals in the HMP were to: generate a comprehensive set of 1,000 reference genomes from organisms comprising the human microbiome; determine whether individuals share a core human microbiome; understand whether changes in the human microbiome can be correlated with changes in human health; and develop new technologies and bioinformatics tools necessary to achieve these goals.
  • Human Microbiome Project: Baylor College of Medicine
    Baylor College of Medicine joined the Genome Sequencing Center at Washington University, the Broad Institute of MIT and Harvard and the J. Craig Venter Institute to address some early goals of this project. The HMP will rely on metagenomic sample sequencing as a key method for comparisons of microbial communities between individuals, sites, and states (e.g., disease, diet, age). Pilot projects will determine the appropriate sequencing platforms, quality controls, and annotation pipelines for (1) generating reference genomes and (2) sequencing metagenomic samples.
  • Human Microbiome Project: The Genome Institute at Washington University School of Medicine in St. Louis
    The Genome Institute is applying next-generation sequencing technology to analyze human metagenomic samples and the genomes of microorganisms that colonize the human body. A number of projects describing the microbiomes from healthy subjects serve to provide baseline information about the role of bacteria, viruses, and eukaryotic microbes in the body. Other projects characterizing the communities they form in a number of diseases ultimately seek to provide doctors with new diagnostic and therapeutic approaches.
  • Human Microbiome Project Data Analysis and Coordination Center (DACC)
    The central repository for all HMP data.
  • International Human Microbiome Project Consortium
    Aims to study and understand the role of the human microbiome in the maintenance of health and causation of disease and to use that knowledge to improve the ability to prevent and treat disease.
  • Human Microbiome Project: The J. Craig Venter Institute
    J. Craig Venter Institute (JCVI) is helping generate a microbial genome reference set of at least 1000 genomes and conduct metagenomic studies to characterize the microbial communities from multiple body sites.
  • The Human Microbiome Project: Facebook

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Last Updated: March 20, 2014