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Researchers working at an NHGRI-supported large-scale sequencing center. Courtesy: The Broad Institute of MIT and Harvard
Feature

Researchers grasp wider role for genetic variation in regulatory elements of genome

Read more Bethesda, Md., Wed., Mar. 4, 2015 - New findings, reported online March 2, 2015 in the journal Nature Genetics, provide new insights into the effects and roles of genetic variation and parental influence on gene activity in mice and humans, as well as the cause of complex traits and disease in both species. Read more


Papers from eMERGE highlight large-scale genomics research

Read moreNearly 20 papers published online in 2014 highlight research on the use of DNA biorepositories and electronic medical records (EMRs) to understand the underlying genomics of disease. The papers appeared in Frontiers in Geneticsand were co-authored by members of the Electronic Medical Records and Genomics (eMERGE) Network, which is supported by NHGRI. Read more

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Featured Grants

  • Centers for Common Disease Genomics (UM1)
    RFA-HG-15-001 [grants.nih.gov]
    Application Receipt Date(s): April 07, 2015
    Expiration Date: April 8, 2015

Highlights

Genome regions linked to BMI and fat distribution

Feet standing on a scaleResearchers have linked multiple new regions of the human genome to body mass index (BMI) and fat distribution, according to two studies just published in Nature. Population Architecture using Genomics and Epidemiology Consortium scientists supported by the National Human Genome Research Institute contributed to the studies that may lead to more effective therapeutic targets. Read more at nature.com: 


Convergent evolution of the genomes of marine animals

cover imageIn a recent paper in Nature Genetics, NHGRI funded researchers compared genomes of whales, dolphins, manatees and walruses to those of their closest land relatives (cow, dog and elephant) and found similar kinds of molecular changes throughout the marine genomes as the animals adapted to sea life. Read the paper: Convergent evolution of the genomes of marine animals. Nature Genetics, January 26, 2015.


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Last Updated: March 4, 2015