Research Funding
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Researchers working at an NHGRI-supported large-scale sequencing center. Courtesy: The Broad Institute of MIT and Harvard
Feature

GM8: Looking across genomic medicine's gaps and opportunities

Read moreOn June 8-9, international experts discussed the gaps, challenges and opportunities in genomics at Genomic Medicine Meeting VIII: NHGRI's Genomic Medicine Portfolio, sponsored by the National Human Genome Research Institute, part of the National Institutes of Health (NIH), and held in Rockville, Maryland. In a series of nine panels, speakers addressed topics of broad interest across NHGRI programs, including interpreting genomic variants, handling genomic data, and diversity in research populations. Read more


Peering at brain and skin cancers through a genomic lens

Read moreA pair of studies from investigators with The Cancer Genome Atlas (TCGA) Research Network has provided new insight into the genomic workings of the deadly types of brain and skin cancer. The findings point to new ways of classifying these cancers based on genomics, which should lead to smarter ways to predict disease behavior and better decisions about treatment. The results were reported in the June 18, online edition of Cell. Read more

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Featured Grants

  • High Quality Human and Non-Human Primate Genome Sequences (U24)
    RFA-HG-15-027 [grants.nih.gov]
    Application Due Date(s): August 25, 2015
    Expiration Date: August 26, 2015

     
Highlights

New view of RNA may help in understanding gene controls

Nature Genetics coverRibonucleic acid (RNA) transmits genetic information from DNA to the cell's protein-producing machinery. RNAs adopt specific physical structures to control when genes are turned on and off. Scientists have now devised a way to view RNA structures in living cells. The new approach, developed at Stanford University with NHGRI support, may greatly improve understanding of gene regulation in biology and medicine.
Read the paper: Structural imprints in vivo decode RNA regulatory mechanisms. Nature, March 18,  2015.


Genome regions linked to BMI and fat distribution

Feet standing on a scaleResearchers have linked multiple new regions of the human genome to body mass index (BMI) and fat distribution, according to two studies just published in Nature. Population Architecture using Genomics and Epidemiology Consortium scientists supported by the National Human Genome Research Institute contributed to the studies that may lead to more effective therapeutic targets. Read more at nature.com: 


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Last Updated: July 6, 2015