Research at NHGRI
The Division of Intramural Research conducts a broad program of laboratory and clinical research.

Dogs mayhelp researchers sniff out new cancer detection and treatment strategies

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Scientists at NIH, Purdueand Tufts University have discovered that a genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers. Find their research in the March 12, 2015, advance online issue ofMolecular Cancer Research. NHGRI's Heidi Parker, Ph.D., and Elaine Ostrander, Ph.D., chief of NHGRI's Cancer Genetics and Comparative Genomics Branch, contributed to the research.Read more

NIH researchers reveal link between powerful gene regulatory elements and autoimmune diseases

Read more Bethesda, Md., Tues., Jan. 28, 2015 - Investigators with the National Institutes of Health (NIH) have discovered the genomic switches of a blood cell are key to regulating the human immune system. The findings, published in Nature today, open the door to new research and development in drugs and personalized medicine to help those with autoimmune disorders such as inflammatory bowel disease or rheumatoid arthritis. Read more

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New on GenomeTV

Trent Lecture: The Complexity of Genetic Susceptibility to Cancer Read more

On Feb. 11, 2015, Stephen J. Chanock, M.D., National Cancer Institute, delivered the 11th Jeffrey M. Trent Lecture in Cancer Research. A video of the lecture is now available on GenomeTV. The Trent Lectureship is presented by the National Human Genome Research Institute's Division of Intramural Research. See the video

NIH researchers publish comprehensive taxonomy and genetic analysis of skin microbial diversity

Read moreA team led by Julie Segre, Ph.D., chief of NHGRI's Translational and Functional Genomics Branch and Heidi Kong, M.D., investigator in the dermatology branch of the National Cancer Institute's Center for Cancer Research, produced an article published in the Oct. 2, 2014 issue of Nature reporting on their study of the genetic content of bacteria, viruses, fungi and other microorganisms on the skin of healthy individuals. The authors performed DNA sequencing of the collection of genomes, or metagenome, of 18 sampling sites across the skin, revealing that each individual has a unique skin microbiota.Read more

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Last Updated: April 3, 2015