Search Results
Research at NHGRI
NHGRI center focused on computationally intensive approaches to analyze large-scale genomic data and identifying genetic contributions to human disease.
… of computationally intensive approaches to analyze large-scale genetic and genomic data, with a particular focus on … human genome sequence. By developing new computational methods and leveraging emerging genomic technologies, the … dramatically improved the performance of genome sequencing methods, uncovering the genomes of thousands of species and …
Research Funding
A collaborative large-scale genome sequencing effort to identify rare risk and protective variants contributing to multiple common disease phenotypes.
… for Common Disease Genomics (CCDG) are a collaborative large-scale genome sequencing effort to comprehensively identify … Collaborative large-scale genome sequencing effort to identify rare risk and … A collaborative large-scale genome sequencing effort to identify rare risk …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… began with a pilot to  assessed the feasibility of a full-scale effort to systematically explore the entire spectrum of … the application of genome analysis technologies, including large-scale genome sequencing. … of cancer using genome analysis technologies, including large-scale genome sequencing. …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… Michele Ramsay, Bamidele Tayo Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry — … Diversity in Cancer Epidemiology Cohorts and Novel Methods to Improve Polygenic Risk Scores Massachusetts … Members of the Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work …
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… CLINSEQ®: A Large-Scale Medical Sequencing Clinical Research Pilot Study …
FAQ
On October 10, 2024, NHGRI hosted a pre-application webinar for the Population Genomic Screening in Primary Care NOFOs: RFA-HG-24-021, RFA-HG-24-022, and RFA-HG-24-023. These FAQs contain questions answered during that webinar.
… for sample collection and shipment? The type of collection methods will be decided by the network during the first year. … reporting of secondary findings not included in the screening protocol at the end of the study as consistent with … the services will be offered also in Spanish? Offering screening in Spanish is a possibility to be discussed by the …
Event
Join us on Wednesday, May 25, as scholars and scientists answer audience questions and address the complexities surrounding historical and present-day eugenics and scientific racism in the context of existing and developing genetic and genomic screening technologies.
… cost-effective, minimal-risk options for prenatal genetic screening and diagnosis for various conditions (variations) … potential benefits than established prenatal and newborn screening programs. Although the individual and public … are clear, scholars have long debated whether screening and sequencing technologies also perpetuate …
News Release
20 papers published online in 2014 highlight research on DNA biorepositories and electronic medical records to better understand the genomics of disease.
… examine the genome in many different ways, and include large patient data sets and diverse ancestries." Some of the papers explore research methods or offer reviews of previously published research in … The findings are important early steps toward developing screening methods for individuals who are at risk for severe …
News Release
The National Human Genome Research Institute (NHGRI) has announced plans to establish a new precision health research program within its Division of Intramural Research.
… Program aims to capitalize on growing availability of large-scale genomic and health record data worldwide to advance the … computation, and data science have enabled the growth of large genomic datasets, with DNA from hundreds of thousands … researchers. One core will provide access to the large datasets emanating from various cohort studies …
… ​Genetic Screening … Genetic screening is the process of testing a population for a …