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Research Funding
Expired Funding Opportunity Announcements dating back to 1994, including Requests for Application, Program Announcements and Notices.
… Optional)" RFA-HG-21-026 : Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project (U24 Clinical Trials Not …
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… s (e.g. BAM /CRAM files, VCF, phenotypic data , gene expression data, peak calls, signal tracks ) will be … the genomic research community: 1000 G enome s, eMERGE , GTEx and ENCODE . Also , it is anticipated that the data from …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… signs of damage. Their metabolism and pattern of gene expression were different from those of healthy cells, … The research team reported that the metabolism and gene expression of the crucial TFH cells are still "largely … transcription factor known as Blimp1. TCF1 turns off expression of Blimp1, just as Blimp1 turns off expression of …
News Release
In a new large-scale genetic analysis, National Institutes of Health (NIH) scientists have found set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type 2 diabetes.
… the largest sequenced-based analysis of microRNA expression in human pancreatic islets to date,” said Francis … the stage for understanding how microRNAs fine-tune gene expression in pancreatic islets and its implications for … the largest sequenced-based analysis of microRNA expression in human pancreatic islets to date. The results of …
The Genomics Landscape
In the September 2023 edition of The Genomics Landscape, NHGRI Director Eric Green, recaps the April 2023 virtual reunion of the leaders of the five genome-sequencing centers (G5), where they tell the untold story on how they ushered the Human Genome Project across the finish line in 2003.
… disease. All the best, … Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant …
News Release
Researchers have found powerful clues to why certain processes and systems in the mouse are so different from those in people.
… However, they also uncovered many DNA variations and gene expression patterns that are not shared, potentially limiting … researchers found that differences appeared in specific tissue and cell types. "We didn't know before these results … sites (which identify regulatory DNA) in 45 mouse cell and tissue types to those in humans. They reported in Science …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data.
… the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene … University of Massachusetts Medical School Rules Of Gene Expression Modeled On Human Dendritic Cell Response To …
News Release
NHGRI awards $6.7 million in new research grants to develop DNA sequencing technologies that are more sensitive, faster, cheaper and more accurate.
… lead to imprecise and incomplete read-outs of gene expression and transcript diversity. Additionally, this way … than the genome in certain cases," he said. "Gene expression in a cancer cell is going to be different than in …
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… Slides_Epigenetic effects and gene expression.pptx …