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Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… The NIH Intramural Sequencing Center (NISC) , established in 1997, is a … genomics facility that emphasizes the generation and analysis of DNA sequence. In addition to providing …
News Release
20 papers published online in 2014 highlight research on DNA biorepositories and electronic medical records to better understand the genomics of disease.
… 2014 highlights research on the use of DNA biorepositories and electronic medical records (EMRs) to better understand … examine the genome in many different ways, and include large patient data sets and diverse ancestries." Some of the … … Related Content … eMERGE publications highlight large-scale genomics research using electronic medical records … 20 …
Staff
Dr. Sergey Koren is an associate Investigator in the Genome Informatics Section of the Center for Genomics and Data Science Research.
… development and pioneered the use of single-molecule sequencing for the reconstruction of complete genomes. In … Koren researches algorithms for the efficient analysis of large-scale genomic datasets with a focus on genome assembly. …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
… variants associated with blood lipid levels. … In a large-scale study of people from diverse ancestries, researchers … that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated …
News Release
The National Human Genome Research Institute (NHGRI) has announced plans to establish a new precision health research program within its Division of Intramural Research.
… … Program aims to capitalize on growing availability of large-scale genomic and health record data worldwide to advance the science of …
Research Funding
Coordinates activities across the Genome Sequencing Program components
… The National Human Genome Research Institute's Genome Sequencing Program Coordinating Center (GSPCC) was funded in … Program components. … The GSPCC has both scientific and administrative activities including: Tracking genome sequencing and analysis costs; data production and deposition; project …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… the project took on a wide range of other goals, from sequencing the genomes of model organisms to developing new … and rat April 2003 Functional Analysis Develop genomic-scale technologies High-throughput oligonucleotide synthesis … Microarray:  Microarrays are devices used in many types of large-scale genetic analysis. They can be used to study how …
About Genomics
An interactive timeline listing key moments from the history of the project.
… hold " The Santa Cruz Workshop " on human genome sequencing. In March 1986, the DOE Office of Health and … uses sequence-tagged sites as the landmarks to help order large segments of DNA. The map in 1995 is a significant … 24 hours of being generated by federally funded large-scale human sequencing centers. The "Bermuda Principles" are …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Office of Scientific Core Facilities.
… in 1993. At the NHGRI, Dr. Elkahloun started applying large scale screening methods to identify genes associated with … DS, Elkahloun AG, Singh LN, Lee-Lin SQ; NISC Comparative Sequencing Program, Kolodgie FD, Cheng Q, Zhao X, Chen MY, …
News Release
NHGRI will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases.
… National Institutes of Health will fund a set of genome sequencing and analysis centers whose research will focus on … costs dropped, the GSP focused much of its efforts on large-scale genome sequencing projects, most recently organized as …