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Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
… … Breast Cancer, Prostate Cancer, Genetic Mutation, Genes, DNA Repair, Family Health History … BRCA1 and BRCA2 are the … of breast cancer and ovarian cancer. People with mutations in either BRCA1 or BRCA2 have a much higher risk for … in the genes. Both BRCA1 and BRCA2 normally act as tumor suppressors, meaning they help to regulate cell …
Outreach
National DNA Day commemorates the successful completion of the Human Genome Project in 2003 and the discovery of DNA's double helix in 1953.
… National DNA Day is a unique day when students, teachers and the … commemorates the completion of the Human Genome Project in 2003 and the discovery of DNA's double helix in 1953. … National DNA Day commemorates …
Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique. DNA, along with the instructions it contains, is passed from … adult organisms to their offspring during reproduction. … In organisms called eukaryotes, DNA is found inside a special …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… and Ph.D. from The Indian Institute of Science, India in 1983. He completed his postdoctoral training at the … and endocrine pancreas, and caused by mutations in a novel tumor suppressor gene, MEN1 . This research effort in the … Because FA is caused by mutations in at least 16 genes in DNA repair pathways, nearly half of FA patients lack proper …
Talking Glossary
Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule.
… Nanopore DNA Sequencing … Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. … Nanopore DNA sequencing is a laboratory …
Talking Glossary
cDNA (short for copy DNA; also called complementary DNA) is synthetic DNA that has been transcribed from a specific mRNA through a reaction using the enzyme reverse transcriptase
… cDNA (copy DNA) … cDNA (short for copy DNA; also called complementary DNA) is synthetic DNA that has … Scientists often synthesize and use cDNA as a tool in gene cloning and other research experiments. … cDNA (short …
Staff
Dr. Bell is a senior investigator at the National Human Genome Research Institute's Cancer Genetics and Comparative Genomics Branch.
… Institutes of Health. She received her B.Sc. (Honors) in Zoology and Genetics and her Ph.D. in Biology and … to home in on regions of the genome containing putative tumor suppressor genes. While at Massachusetts General … DeLoia JA, Bell DW, and Elnitski L. Recurrent patterns of DNA methylation in the ZNF154, CASP8 and VHL promoters across …
News Release
On April 25, National DNA Day, the National Institutes of Health (NIH) will welcome a new statue, “The Ladder,” celebrating DNA and children.
… about genomics through sculpture. … On April 25, National DNA Day, the National Institutes of Health (NIH) will welcome … commemorates the completion of the Human Genome Project in 2003 and the discovery of DNA's double-helical structure … the profound effect that her project “Mamorial,” a breast cancer initiative that invites breast cancer survivors to …
Talking Glossary
La hibridación fluorescente in situ (FISH) es una técnica de laboratorio que se usa para detectar y localizar una secuencia de ADN específica en un cromosoma.
… Hibridación fluorescente in situ (FISH) … La hibridación fluorescente in situ (FISH) … laboratory technique used to detect and locate a specific DNA sequence on a chromosome. In this technique, the full set … and then exposed to a “probe”—a small piece of purified DNA tagged with a fluorescent dye. The fluorescently labeled …
Genomics Teaching Tool
An activity that demonstrates how DNA can be isolated from a strawberry using common household items.
… plants, animals and bacteria. Deoxyribonucleic acid , or DNA, is the molecule that controls everything that happens in the cell. DNA contains instructions that direct the activities of cells …