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Staff
Vence Bonham is the acting deputy director for NHGRI and an associate investigator in NHGRI's Social and Behavioral Research Branch. ​
… methods and data types including qualitative interviews, quantitative survey methods, and biological data including … populations.  The Bonham group also studies sickle cell trait and sickle cell disease, a condition with applications … GJ, Brody LC. Screening student athletes for sickle cell trait--a social and clinical experiment.  N Engl J Med , …
Educational Resources
Gene regulation is the process of turning genes on and off.
… is the process of turning genes on and off. … Gene Expression, Genes, DNA, Transcription Factors … Gene …
Educational Resources
The Y chromosome is one of the two sex chromosomes that are involved in sex determination.
… X Chromosome, Y Chromosome, Phenotype, Fragile X Syndrome, Trait … The Y chromosome is one of the two sex chromosomes …
Educational Resources
Chromatin is a substance within a chromosome consisting of DNA and protein.
… of DNA and protein. … Chromosome, Histones, Gene Expression, DNA … Chromatin refers to a mixture of DNA and …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… product or a change in the cell. … Biochemistry, Gene Expression, Metabolism, Medication … A biological pathway is …
Educational Resources
A histone is a protein that provides structural support to a chromosome.
… chromosome. … Histones, DNA, Chromatin, Double Helix, Gene Expression … A histone is a protein that provides structural … shape. Histones also play a role in the regulation of gene expression. … Educational Resources …
Clinical Research
The INSIGHTS study is exploring sickle cell disease in adults.
… Health Information About Sickle Cell Disease Sickle Cell Trait National Human Genome Research Institute - Learning … Disorder, Clinical Trial, Research Study, Sickle Cell Trait … The INSIGHTS study is exploring sickle cell disease …
The Genomics Landscape
In the January 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly developed polygenic risk scores webpage, which provides graphical and textual information about polygenic risk scores, describes polygenic traits, introduces how polygenic risk scores can be calculated, and explains how such scores can be interpreted.
Educational Resources
Nucleic acids are large biomolecules that play essential roles in all cells and viruses.
… Nucleotide, Genetic Code, DNA, Deoxyribonucleic Acid, Gene Expression … Nucleic acids are large biomolecules that play … A major function of nucleic acids involves the storage and expression of genomic information. Deoxyribonucleic acid, or …
Educational Resources
Genomics refers to the study of the entire genome of an organism whereas genetics refers to the study of a particular gene.
… to the study of a particular gene. … Genomics, Genes, Gene Expression, Human Genome Project … Genomics is a field of …