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TCGA researchers identify potential drug targets, markers for leukemia risk

Bethesda, Md., Wed., Mayl 1, 2013 - Investigators for The Cancer Genome Atlas (TCGA) Research Network have detailed and broadly classified the genomic alterations that frequently underlie the development of acute myeloid leukemia (AML), a deadly cancer of the blood and bone marrow. Their work paints a picture of a cancer marked by relatively few mutations compared to other types of cancer occurring in adults. (Read more)

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• New England Journal of Medicine Series on Genomic Medicine
  A series of articles on the quest to screen, prevent and treat disease in the new world of genomic medicine.

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Genome Advance of the Month

Grabbing hold of cells and tissues with zinc fingers

Zinc fingers are a potential tool in certain disease therapies because they could target defective copies of genes. This month's Genome Advance of the Month describes new uses for zinc fingers to improve researchers' ability to study the processes of single cells and the interactions between larger groups of cells.  Read more

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Recent Research Papers of Interest

• NT5E Mutations and Arterial Calcifications
  NEJM, Feb. 2, 2011
• Comparative and demographic analysis of orang-utan genomes
  Nature, Jan. 27, 2011

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  Last Updated: April 23, 2013

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