Feature

Newly Identified Genes Influence Insulin and Glucose Regulation

Bethesda, Md., Tues., Jan. 19, 2010 — An international research consortium finds 13 new genetic variants that influence blood glucose regulation, insulin resistance and the function of insulin-secreting beta cells in populations of European descent. Five of the newly discovered variants increase the risk of developing type 2 diabetes, the most common form of diabetes in the United States and worldwide. The results of two studies, conducted by the Meta-Analyses of Glucose and Insulin Related Traits Consortium (MAGIC), provide important clues about the role of beta cells in the development of type 2 diabetes. The studies, funded in part by the National Institutes of Health, appeared online Jan. 17, 2010, in Nature Genetics. (more)

Highlights

Read the papers related to our featured news release:

• Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
  Nature Genetics, Jan. 17, 2010
  
  
• New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
  Nature Genetics, Jan. 17, 2010
  
  
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Last Updated: January 19, 2010

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