Last updated: March 23, 2012
National Human Genome Research Institute
National Human Genome Research Institute
Director's Report Related Documents: September 2005
Ethics/Conflict of Interest
Requests for Information (RFI)/Notices (NOT)
- Request for Information: Comments on the Identification of Mendelian Disorders by Genomic Sequencing [grants1.nih.gov]
- Notice of Intent to Publish Four Requests for Applications (RFAs) for Knockout Mouse Project (KOMP) [grants1.nih.gov]
Sequencing Status update
- Current Mechanism Table
- News Release: NHGRI Selects 13 New Targets For Large-Scale Sequencing Program
Large-Scale Sequencing Concept Clearance
- Large-Scale Sequencing Concept Clearance, September 2005 National Advisory Council for Human Genome Research
September 12-13, 2005
Sequencing Meetings
Chimp Genome Analysis Published
- News Release: New Genome Comparison Finds Chimps, Humans Very Similar at the DNA Level
- Initial sequence of the chimpanzee genome and comparison with the human genome
Nature, September 2005
$1000 and $100,000 Genome Sequencing Technology Grants Awarded
New, Superfast Sequencing Methods
- Genome sequencing in microfabricated high-density picolitre reactors [nature.com]
- Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome [sciencemag.org]
- Cut-Rate Genomes on the Horizon?
- Superfast DNA sequencing [usnews.com]
NCI/NHGRI Collaboration on Cancer Sequencing Meeting
- Tackling the Cancer Genome [sciencemag.org]
Multi-Species Genome Comparisons
- News Release: Multi-Species Genome Comparison Sheds New Light On Evolutionary Processes, Cancer Mutations
- Dynamics of Mammalian Chromosome Evolution Inferred from Multispecies Comparative Maps [sciencemag.org]
Anti-Cancer Drugs May Hold Promise for Progeria
- News Release: Anti-Cancer Drugs May Hold Promise for Premature Aging Disorder
- Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation
- Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes
- Inhibiting farnesylation of progerin prevents the characteristic characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome
Action Items of Interest
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