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The NIH Common Fund Undiagnosed Diseases Network

In 2008, the NIH Undiagnosed Diseases Program (UDP) was organized and established by the National Human Genome Research Institute (NHGRI), the National Institute of Health (NIH) Office of Rare Diseases Research (ORDR) and the NIH Clinical Center to help provide diagnosis and treatment for patients with unknown disorders.

In 2012, building on the success of this program in diagnosing both known and new diseases, the NIH Common Fund's Undiagnosed Diseases Network (UDN) was created to test whether this type of cross-disciplinary approach to disease diagnosis is feasible to implement in academic medical centers around the United States.

The NIH Common Fund Undiagnosed Diseases Network will promote the use of genomic data in disease diagnosis and will engage basic researchers to elucidate the mechanisms underlying the diseases so that treatments may be identified. The program will also train clinicians in the use of contemporary genomic approaches so that genomic methods can increasingly be brought to bear on myriad diseases.

Funding Opportunity Announcements (FOAs)

• RFA-RM-13-003 [grants.nih.gov]: Undiagnosed Diseases Gene Function Research (R21)
  Release Date(s): June 14, 2013
   
• RFA-RM-12-020 [grants.nih.gov]: Coordinating Center for an Undiagnosed Diseases Network (UDN) (U01)
  Release Date: November 30, 2012 
   
• PA-13-076 [grants.nih.gov]: Gene Function Studies to Investigate Rare and Undiagnosed Diseases (Admin Supp)
  Release Date: January 7, 2013
   
• RFA-RM-13-004 [grants.nih.gov]: Clinical Sites for an Undiagnosed Diseases Network (UDN) (U01)
  Release Date: January 29, 2013
   
  • NOT-RM-13-014 [grants.nih.gov] Notice Announcing Frequently Asked Question (FAQs) and Applicant Information Webinar for RFA-RM-13-004 "Clinical Sites for an Undiagnosed Diseases Network (UDN) (U01)"
    Release Date: March 22, 2013
     

Gene Function Studies to Investigate Rare and Undiagnosed Diseases
The current list of genes and diseases of interest to the Undiagnosed Diseases Network (UDN) for the FOA PA-13-076 [grants.nih.gov].

For more information, see: Undiagnosed Diseases Network [commonfund.nih.gov]

Last Updated: April 5, 2013