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Researchers discover underlying genetics, marker for stroke, cardiovascular disease

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Bethesda, Md., Thurs., March 20, 2014 - Scientists studying the genomes of nearly 5,000 people have pinpointed a genetic variant tied to an increased risk for stroke, and have also uncovered new details about an important metabolic pathway that plays a major role in several common diseases. Together, their findings may provide new clues to underlying genetic and biochemical influences in the development of stroke and cardiovascular disease, and may also help lead to new treatment strategies. Read more


NIH team discovers genetic disorder causing strokes and vascular inflammation in children

Read moreBethesda, Md., Wed., Feb. 19, 2014 - National Institutes of Health researchers have identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood. The team's discovery coincides with findings by an Israeli research group that identified an overlapping set of variants of the same gene in patients with a similar type of blood vessel inflammation.  Read more


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Highlights

Genome Advance of the Month

Circulating tumor DNA: A new generation of cancer biomarkers

February'sRead more Genome Advance of the Month describes a new study, published in the February 19, 2014, issue of Science Translational Medicine, which examines the potential of screening ctDNA for somatic mutations as a way to detect and follow the progression of a patient's tumor. Read more 
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Last Updated: March 20, 2014