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A new role for zebrafish: larger scale gene function studies

Read more Bethesda, Md., Fri., June 5, 2015 - A relatively new method of targeting specific DNA sequences in zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health. Read more


NIH researchers pilot predictive medicine in study of healthy people's DNA

Read more Bethesda, Md., Thurs., June 4, 2015 - A new NIH study has turned traditional genomics research on its head. Instead of trying to find a mutation in the genomic sequence of a person with a genetic disease, researchers sequenced the genomes of healthy participants and analyzed the data to find presumed mutations that would almost certainly lead to a genetic condition. Results were published today in the American Journal of Human Genetics. Read more

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Highlights
Genome Advance of the Month

Gene-disease association data could improve drug development

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Drug development is a risky business. More than half of candidate drugs that look promising in the research lab will ultimately fail. More than a quarter of drugs that reach the clinical trial stage will be rejected as ineffective. June's Genome Advance of the Month focuses on how drug development success rates could be improved by using known genetic associations to help choose research targets. Read more

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Last Updated: July 30, 2015