Research Funding Opportunities

To apprise the community of research areas that support that mission, NHGRI periodically publishes funding opportunities in the NIH Guide for Grants and Contracts. For your convenience, we have also listed the funding opportunities related to NHGRI on this webpage. NHGRI welcomes innovative investigator-initiated applications and encourages investigators with novel ideas to discuss potential applications with program staff during the concept development stage of the application. If you are considering applying for a Program Announcement with special review (PAR), a Request for Applications (RFA), or an application that exceeds $500K in direct cost in any one year, we encourage you to review the Guidance to Potential Applicants for NHGRI Support.

For how NHGRI will treat new and non-competing applications, see the FY2023 Funding Policy.

• RFA-HG-24-001: Research on the Impact of and Methods for Implementing Regional Genomic Medicine eConsult Services (U01 Clinical Trials Optional)
  Application Due Date(s): May 30, 2024
  Expiration Date: May 31, 2024
   
• PAR-24-106: Solutions to Enable Regional Genomic Medicine eConsult Services (R43/R44 Clinical Trial Optional)
  Application Due Date(s): May 30, 2024
  Expiration Date: May 31, 2024
   
• PAR-24-107: Solutions to Enable Regional Genomic Medicine eConsult Services (R41/R42 Clinical Trial Optional)
  Application Due Date(s): May 30, 2024
  Expiration Date: May 31, 2024
   
• RFA-HG-23-033: Advancing Genomic Medicine Research (R21 Clinical Trial Optional)
  Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025
  Expiration Date: February 12, 2025
   
• PAR-23-301: Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)
  Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026
  Expiration Date: January 8, 2027
   
• RFA-HG-23-017: Investigator-Initiated Research in Genomics and Health Equity (R01 Clinical Trial Optional)
  Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal)
  Expiration Date: July 09, 2025
   
• RFA-HG-23-018: Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional)
  Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal)
  Expiration Date: July 09, 2025
• NOT-HG-24-008: Notice of Extension of the First Receipt Date of RFA-HG-23-018: Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial (Clinical Trial Optional)
• NOT-HG-23-049: Notice of Pre-Application Webinar for the Investigator-Initiated Research in Genomics and Health Equity: RFA-HG-23-017 (R01 Clinical Trial Optional) and RFA-HG-23-018 (R21 Clinical Trial Optional)
• NOT-HG-24-032: Notice of Change to NHGRI-specific language in RFA-HG-23-018, Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional)
   
• PAR-23-184: Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
  Application Due Dates: Applications are accepted by continuous receipt and are due by 5:00 PM local time of applicant organization. 
  Expiration Date: July 09, 2026
   
• PAR-23-098: Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
  Application Due Date: June 23, 2023, June 21, 2024
  Expiration Date: June 22, 2024
   
• NOT-HG-23-028: Notice of Intent to Publish a Funding Opportunity Announcement for Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed)
   
• RFA-HG-22-026: Diversity Centers for Genome Research (U54 Clinical Trials Optional)
  Application Due Dates: December 6, 2022; June 23, 2023; June 24, 2024
  Expiration Date: June 25, 2024
   
• RFA-HG-22-027: Diversity Centers for Genome Research (UG3/UH3 Clinical Trials Optional)
  Application Due Dates: December 6, 2022; June 23, 2023; June 24, 2024
  Expiration Date: June 25, 2024
   
• Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
  PAR-22-107
  Application Receipt Date(s): June 21, 2024
  Expiration Date: June 22, 2024
   
• Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients’ Use of Genomic Information
  NOT-HG-22-011
   
• Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
  PAR-21-254
  Application Due Dates: February 5, June 5, October 5
  Expiration Date: September 8, 2024
• NOT-HG-24-033: Notice to change the expiration date of PAR-21-254: Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
   
• Investigator Initiated Research in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed)
  PAR-21-255
  Application Due Dates: February 16, June 16, October 16
  Expiration Date: September 8, 2024
• NOT-HG-24-034: Notice to change the expiration date of PAR-21-255: Investigator Initiated Research in Computational genomics and Data Science (R21 Clinical Trial Not Allowed)
   
• Notice of Special Interest: Development of Statistical, Population Genetics and Computational Methods Related to Polygenic Prediction of Health and Disease in Diverse Populations
  NOT-HG-20-010
   
• Notice of New NIH-Designated Data Repository: NHGRI’s Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)
  NOT-HG-19-02

• PA-23-217: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity)
  Application Due Date(s): December 08, 2023, April 08, 2024, August 08, 2024​​​​​​, December 08, 2024, April 08, 2025​​​​​​​, August 08, 2025
  Expiration Date: September 08, 2025​​​​​​​
   
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)
  PAR-21-357
  Expiration Date: January 8, 2025
   
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
  PAR-22-060
  Expiration Date: January 8, 2025
   
• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
  PA-21-268 
  Expiration Date: June 30, 2024
   
• Plans to Promote Safe Environments at Conferences Supported by NIH Grants and Cooperative Agreements
  NOT-OD-22-074

• NOT-TR-23-026: Notice of Special Interest (NOSI): Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3) (Clinical Trial Optional) for Advancing Recruitment through Trial Innovation Network (AR-TIN)
   
• PAR-23-124: Genomic Community Resources (U24 Clinical Trial Not Allowed)
  Application Due Date(s): May 25, 2023, September 25, 2023, January 25, 2024, September 25, 2024, January 25, 2025, September 25, 2025, January 25, 2026
  Expiration Date: January 26, 2026
   
• PAR-23-219: PAR-SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)
  Application Due Date(s): September 5, 2023, January 5, 2024, April 5, 2024, September 5, 2024, January 5, 2025, April 5, 2025
  Expiration Date: April 6, 2024
   
• PAR-23-220: SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1 Clinical Trial Required)
  Application Due Date(s): September 5, 2023, January 5, 2024, April 5, 2024, September 5, 2024, January 5, 2025, April 5, 2025
  Expiration Date: April 6, 2024
   
• PAR-23-166: Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
  Application Due Date(s): July 08, 2024, July 08, 2025, July 08, 2026
  Expiration Date: August 08, 2026
   
• NOT-OD-23-106: Revising the NIH/AHRQ/NIOSH Post-Submission Material Policy
   
• PAR-23-138: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
   
• NOT-OD-23-073: Notice of Special Interest (NOSI): Administrative Supplements to Enhance Software Tools for Open Science
   
• NOT-OD-23-098: Notice of Special Interest: Administrative Supplements to NIH-funded T32 and TL1 Training Grants to Better Integrate Behavioral and Social Sciences (BSS) with other Health-Related Sciences
   
• PAR-23-120: Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)
  Application Due Date(s): May 15, 2023, May 15, 2024, May 15, 2025
  Expiration Date: May 16, 2025
   
• The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)
  RFA-OD-22-028
  Application Due Date(s): December 19, 2022, November 22, 2023; November 22, 2024
  Expiration Date: November 23, 2024
   
• Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations
  NOT-MD-22-012
   
• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
  PAR-22-105
  Application Due Date(s): June 15, 2022, October 05, 2022, February 05, 2023, June 05, 2023, June 05, 2023, February 05, 2024, June 05, 2024, October 05, 2024, February 05, 2025
  Expiration Date: May 8, 2025
   
• Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
  PAR-22-106
  Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, February 16, 2025, June 16, 2025
  Expiration Date: September 8, 2025
   
• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
  PAR-22-109
  Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, October 16, 2024
  Expiration Date: February 16, 2025
   
• International Bioethics Research Training Program (D43 Clinical Trial Optional)
  PAR-22-116
  Application Receipt Date(s): June 6, 2024
  Expiration Date: June 7, 2024
   
• International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)
  PAR-22-118
  Application Receipt Date(s): June 6, 2024
  Expiration Date: June 7, 2024
   
• Notice of Intent to Publish a Funding Opportunity Announcement for a Data Management and Coordinating Center for Diagnostic Centers of Excellence (U2C Clinical Trial Not Allowed) NOT-NS-22-071
   
• Notice of Special Interest (NOSI): Administrative Supplements to Support Enhancement of Software Tools for Open Science NOT-OD-22-068
   
• Notice of Special Interest (NOSI): Administrative Supplements to Support Collaborations to Improve the AI/ML-Readiness of NIH-Supported Data NOT-OD-22-067
   
• Notice of Special Interest (NOSI): Support for existing data repositories to align with FAIR and TRUST principles and evaluate usage, utility, and impact NOT-OD-22-069
   
• Notice of Special Interest (NOSI): Administrative Supplements for Advancing the Ethical Development and Use of AI/ML in Biomedical and Behavioral Sciences NOT-OD-22-065
   
• Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed) NOT-HL-23-001
   
• Administrative Supplements to Promote Diversity in Research and Development Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 Application Due Dates: Rolling
  Expiration Date: September 10, 2024
   
• Notice Announcing the National Human Genome Research Institutes Expectation for Sharing Quality Metadata and Phenotypic Data NOT-HG-21-022
   
• Notice of NIH Participation in Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science NOT-OD-21-011
   
• Notice of Special Interest (NOSI): Administrative Supplements to Support Enhancement of Software Tools for Open Science NOT-OD-20-073
   
• Announcing the High-Priority, Short-Term Project Award (R56) 
  • Notice of NHGRI's Participation in NOT-OD-04-047 "High Priority, Short-Term Project Award (R56)" 
    NOT-HG-17-004 [grants.nih.gov]