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Research Projects

Genetic diseases affect millions of Americans every day, and research is key to improving our ability to diagnose and treat these diseases. At the National Human Genome Research Institute, our researchers are creating foundational tools and methods to expand genomics research, ultimately leading to medical breakthroughs.

Atlas
Atlas of Human Malformation Syndromes in Diverse Populations

A photo atlas of individuals from diverse populations who are affected by malformation syndromes.

Woman
Breast Cancer Information Core (BIC)

A central repository for information regarding mutations and polymorphisms in breast cancer susceptibility genes.

chromosomes
Clinical Genomic Database (CGD)

A manually-curated database of all conditions with known genetic causes, focusing on the utility of genetic/genomic diagnosis and the availability of disease-specific interventions.

zebrafish
CRISPRz

A curated database of validated CRISPR targets in zebrafish.

Man looking at proteins
Homeodomain Resource

An annotated collection of non-redundant protein sequences, three-dimensional structures, and genomic information for the homeodomain protein family.

ACTGs
Hydra 2.0 Genome Project Portal

Access to sequence data and related information on Hydra, a valuable experimental model for the study of numerous biological processes.

Pattern of ACTGs
Hydractinia Genome Project Portal

Access to preliminary sequence data and related information on Hydractinia, a model system for the study of fundamental biological processes.

Hands
Limb Morphology Database

Standardized terms used to describe human morphology developed by an international group of clinicians working in the field of dysmorphology.

Mnemiopsis
Mnemiopsis Genome Project Portal

Access to the annotated Mnemiopsis genomic sequence, the first set of publicly available whole-genome sequencing data from any ctenophore species.

Father and son
Multiplex Initiative

A large, multi-disciplinary research collaboration to examine the effects of genetic susceptibility testing for several common health conditions.

Dog
NHGRI Dog Genome Project

Information for researchers and dog owners interested in finding the genetic basis of morphologic traits, behaviors, or diseases in the domestic dog.

Hand
Pallister-Hall Syndrome

Information for professionals and families caring for or affected by Pallister-Hall Syndrome.

A woman's back
Pigment Cell Gene Resource

A centralized, comprehensive resource of published scientific data relevant to pigment cell biology.

Cells
Red Cell Membrane Disorder Mutations Database

A database containing confirmed mutations to inherited disorders of the erythrocyte membrane associated with hemolytic anemia.

Laboratory
Zebrafish Insertion Collection (ZInC)

A Web-based, searchable collection of zebrafish mutations generated by DNA insertion.

Last updated: December 3, 2018