One little fish hooks genome researchers with its versatility

At the largest zebrafish facility in the country, Kevin Bishop, NHGRI Zebrafish Core staff member, holds up a tank of zebrafish to observe their behavior and physiology. Modern molecular biology and the genome of a tiny silver and black striped fish - the zebrafish - are making waves in genomics research. This tiny fish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease. Here, at the National Human Genome Research Institute (NHGRI), researchers are working to advance human health by coupling the potential of this little fish with an institute-funded resource known as The Zebrafish Core.
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The Genomic Landscape of Breast Cancer in Women of African Ancestry

Olufunmilayo Olopade On June 7, Olufunmilayo I. Olopade, M.D., F.A.C.P., presented The Genomic Landscape of Breast Cancer in Women of African Ancestry, the final lecture in the 2016 Genomics and Health Disparities Lecture Series. Dr. Olufunmilayo is director of the Center for Clinical Cancer Genetics at the University of Chicago School of Medicine. She is an expert in cancer risk assessment and treatment for aggressive forms of breast cancer. Watch video | Read about the series

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Investigational Device Exemptions (IDE) and Genomics Workshop

Double helix On Friday, June 10, 2016, the National Human Genome Research Institute (NHGRI) hosted the Investigational Device Exemptions (IDE) and Genomics Workshop. The workshop gathered investigators, institutional review boards (IRB), the FDA and NHGRI to share how to determine whether a study requires an IDE and how to fulfill IDE requirements if the FDA should require an it for research involving the use of genomic technologies. Video is now available. View agenda and videos

New NIH studies seek adults and families affected by sickle cell disease/trait

Red blood cells (left) and sickle cells blocking blood flow (right) People with sickle cell disease (SCD) can experience excruciating pain, kidney problems, a higher risk of stroke and, in rare cases, chronic leg ulcers. Little is known about why the severity of these symptoms varies throughout a lifetime or why these symptoms differ from person to person. NHGRI researchers are seeking help from people affected by SCD to find the factors - environmental, social and genetic - that impact the severity of the symptoms. Read more

GHB chief joins Roundtable on Genomics and Precision Health

Bob Wildin Robert Wildin, M.D., chief of NHGRI's Genomics and Healthcare Branch (GHB), is helping to jumpstart activity in the public health application of genomic medicine as a member of the National Academies' Roundtable on Genomics and Precision Health. Public health initiatives like this have great potential to reach the underserved, he said. The roundtable will issue a new toolkit in 2017. Read more

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