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The National Human Genome Research Institute conducts genetic and genomic research, funds genetic and genomic research and promotes that research to advance genomics in health care.


Diverse group of people

Perspective discusses the importance diversity in research to help further precision medicine

The scientific and ethical benefits of incorporating health information from diverse and underrepresented populations in genomic medicine are described in a Perspective by co-authors Dr. Lucia A. Hindorff and Mr. Vence L. Bonham, NIH's National Human Genome Research Institute, and Dr. Lucila Ohno-Machado, University of California, San Diego. Their recommendations for incorporating diversity into the evidence base for genomic medicine appeared in the Sept. 13, 2018 issue of Future Medicine. Read the Q&A with Dr. Ohno-Machado.

Eric Green

Educational Videos Use Poetry, Dance, Animation and Storytelling to Teach Elements of Genomics

The September issue of The Genomics Landscape highlights five new educational videos that were unveiled as a part of the '15 for 15' celebration to commemorate the 15th annivarsary of the completion of the Human Genome Project. Also highlighted: the new NHGRI-funded Analysis, Visualization, and Informatics Lab-space (AnVIL) initiative, the passing of Professor Bongani Mayosi, and the recent launch of the All of Us Research Hub.

Thanksgiving Dinner

My Family Health Portrait (MFHP) has a new home

Starting September 6, 2018, My Family Health Portrait (MFHP) is moving to the Centers for Disease Control and Prevention's Public Health Genomics Knowledge Base (PHGKB) website. For more than a decade, the tool has been hosted by NHGRI, allowing users to create a family health history to identify inheritance patterns across family members and manage personal disease risk. The My Family Health Portrait tool was developed by NHGRI, the CDC, and other partners.

Nursing professionals

NIH institutes create online Omics Nursing Science & Education Network (ONSEN)

NHGRI, NINR and NCI have created a new website, the Omics Nursing Science & Education Network (ONSEN). Omics is the field of research focused on genomics, metabolomics, proteomics and the microbiome. Initiated from the nursing research genomics community, the website includes a searchable database of Omics projects and aims to foster collaborations among investigators in all disciplines. The website also provides opportunities to identify research mentors and pre/post-doctoral opportunities in Omics.

The image shows an exaggerated immune response in the gut in a mouse model of Activated PI3 Kinase Syndrome, which is associated with increased production of antibodies against both gut bacteria and self (autoantibodies and autoimmunity).

Researchers develop mouse model for study of human immunodeficiency disease

NHGRI and NIAID researchers developed a new mouse model of a human immunodeficiency disease caused by mutations to the gene PI3-kinase delta. Treating these mutant mice with broad antibiotics prevented both the hyper-reactivity of their lymphocytes (white blood cells that are part of the immune system) and the generation of a wide range of autoantibodies. The findings, published in Nature Immunology, have broad implications for a people with immunodeficiencies and autoimmune conditions.