NHGRI logo

The Secondary Genomics Findings Service (SGFS) is a team-based clinical service provided by NHGRI to Intramural Investigators employing exome/genome sequencing to accomplish their research goals. The SGFS will annotate de-identified research exome/genome data for the presence of possible actionable secondary variants. Any secondary variants found in the research data will be clinically confirmed. The SGFS will coordinate confirmatory samples and provide genetic counseling and results disclosure to participants with secondary findings. 

Lab icon
Is the SGFS applicable to my research?

Secondary findings explained, eligible protocols, and services offered

Chat icon
What should I consider before applying?

Responsibilities as a PI, consent, type of data accepted, and how to apply

Around the clock icon
What happens after my protocol is accepted?

How to send data, confirming preliminary results, and returning results

Staff

Service Head

Leslie Biesecker
Leslie G. Biesecker, M.D.
  • NIH Distinguished Investigator
  • Medical Genomics and Metabolic Genetics Branch

Annotation Support

Jennifer Johnston
Jennifer Johnston, Ph.D.
  • Staff Scientist
  • Clinical Genomics Section

Genetic Counselor

Julie Sapp
Julie C. Sapp, Sc.M., C.G.C.
  • Genetic Counselor
  • Clinical Genomics Section

Last updated: June 11, 2020