Is SGFS applicable to my research?
What are secondary findings?
Secondary findings are pathogenic or likely-pathogenic variants in medically actionable genes that are directly searched for in human genomic DNA but are unrelated to the primary indication for sequencing. In other words, secondary findings are genetic predispositions to treatable or preventable diseases that neither participants nor ordering clinicians may have previously been aware of. Following the American College of Medical Genetics guidance for clinical genomic testing, the SGFS currently annotates exome/genome sequencing data you send to us for the 73 genes outlined in Miller et al., 2021.
Last updated: April 13, 2022