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Alexander F. Wilson, Ph.D.

Co-Chief & Senior Investigator, Computational and Statistical Genomics Branch (CSGB)
Head, Genometrics Section

Selected Publications

Wilson AF, Cohen JC.  Hypotheses for testing deviations from random integration: evidence for nonrandom retroviral integration.  Genomics, 3(2):137-142. 2008. [PubMed]

Amos CI, Elston RC, Wilson AF, Bailey-Wilson JE.  A more powerful robust sib-pair test of linkage for quantitative traits.  Genet Epidemiol, 6(3):435-449. 1989. [PubMed]

Wilson AF, Elston RC, Sellers TA, Bailey-Wilson JE, Gersting JM, Deen DK, Sorant AJM, Tran LD, Amos CI, Siervogel RM. Stepwise oligogenic segregation and linkage analysis illustrated with dopamine-beta-hydroxylase activity. Am J Med Genet, 35:425-432. 1990. [PubMed]

Wilson AF, Elston RC, Tran LD, Siervogel RM. Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: application to traits related to hypertension. Am J Hum Genet, 48:862-872. 1991. [PubMed]

Wilson AF, Elston RC.   Statistical validity of the Haseman-Elston sib-pair test in small samples.  Genet Epidemiol, 10(6):593-598. 1993. [PubMed]

Goldin LR, Chase GA, Wilson AF.  Regional inference with averaged P values increases the power to detect linkage.  Genet Epidemiol, 17(3):157-164. 1999. [PubMed]

Wilson AF, Sorant AJ.  Equivalence of single- and multilocus markers: power to detect linkage with composite markers derived from biallelic loci.  Am J Hum Genet, 66(5):1610-1615. 2000.  [PubMed]

Miller NH, Justice CM, Marosy B, Doheny KF, Pugh E, Zhang J, Wilson AF. Identification of candidate regions in familial idiopathic scoliosis. Spine 30(10):1181-1187. 2005. [PubMed]

McMahon FJ, Buervenich S, Charney D, Lipsky R, Rush AJ, Wilson AF, Sorant AJM, Papanicolaou GJ, Laje G, Fava M, Trivedi M, Wisniewski S, Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of citalopram treatment: Results from the STAR*D trial. Am J Hum Genet, 78(5):804-814. 2006. [PubMed]

Miller NH, Marosy B, Justice CM, Novak, SM, Tang, EY, Boyce P, Pettengil J, Doheny, KF, Pugh, EW, Wilson AF. Linkage analysis of genetic loci for kyphoscoliosis on chromosomes 5p13, 13q13.3 and 13q32. Am J Med Genet, 140A(10):1059-1068. 2006. [PubMed]

Roy-Gagnon M-H, Mathias RA, Fallin MD, Jee SH, Broman, KW, Wilson AF. An extension of the regression of Offspring on Mid-Parent method to test for association and estimate locus-specific heritability: The revised ROMP method. Ann Hum Genet, 72:115-25. 2008. [PubMed]

Herrera-Galeano JE, Becker DM, Wilson AF, Yanek LR, Bray P, Vaidya D, Faraday N, Becker LC. A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability. Arterioscler Thromb Vasc Biol, 28:1484-90. 2008. [PubMed]

Biesecker LG, Mullikin JC, Facio FM, Turner C, Cherukuri PF, Blakesley RW, Bouffard GG, Chines PS, Cruz P, Hansen NF, Teer JK, Maskeri B, Young AC, Manolio TA, Wilson AF, Finkel T, Hwang P, Arai A, Remaley AT, Sachdev V, Shamburek R, Cannon RO, Green ED, NISC Comparative Sequencing Program. The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine. Genome Res. 19(9):1665-1674. 2009. [PubMed]

Sung H, Kim Y, Cai J, Cropp CD, Simpson CL, Li Q, Perry BC, Sorant AJM, Bailey-Wilson JE, Wilson AF. Comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression. BMC Proc, 5(Suppl 9): S15. 2011.

Wilson AF, Blangero J, Ziegler A. Lessons learned from Genetic Analysis Workshop 17: Transitioning from genome-wide associations studies to whole-genome statistical genetic analysis. Genet Epidemiol, 35(Suppl 8):S107-14. 2011.[PubMed]

Bailey-Wilson, Wilson AF. Linkage analysis in the next generation sequencing era. Hum Hered, 72(4):228-36. 2011. [PubMed]

Suktitipat B, Mathias RA, Vaidya D, Yanek LR, Young JH, Becker LC, Becker DM, Wilson AF, Fallin MD.  The robustness of generalized estimating equations for association tests in extended family data.  Hum Hered, 74(1):17-26. 2012. [PubMed]

Justice CM, Yagnik G, Kim Y, Peter I, Jabs EW, Erazo M, Ye X, Ainehsazan E, Shi L, Cunningham ML, Kimonis V, Roscioli T, Wall SA, Wilkie AO, Stoler J, Richtsmeier JT, Heuze Y, Sanchez-Lara PA, Buckley MF, Druschel CM, Mills JL, Caggana M, Romitti PA, Kay DM, Senders C, Taub PJ, Klein OD, Boggan J, Zwienenberg-Lee M, Naydenov C, Kim J, Wilson AF, Boyadjiev SA.  A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9.  Nat Genet, 44(12):1360-1364. 2012. [PubMed]

Kirino Y, Zhou Q, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Ugurlu S, Erer B, Abaci N, Ustek D, Meguro A, Ueda A, Takeno M, Inoko H, Ombrello MJ, Satorius CL, Maskeri B, Mullikin JC, Sun HW, Gutierrez-Cruz G, Kim Y, Wilson AF, Kastner DL, Gul A, Remmers EF.  Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behcet disease.  Proc Natl Acad Sci USA, 110(20):8134-8139. 2013. [PubMed

Pemov A, Sung H, Hyland PL, Sloan JL, Ruppert SL, Baldwin AM, Boland JF, Bass SE, Lee HJ, Jones KM, Zhang X, Mullikin JC, Widemann BC, Wilson AF, Stewart DR. Genetic Modifiers of Neurofibromatosis Type 1-Associated Cafe-au-Lait Macule Count Identified Using Multi-platform Analysis. PLoS Genet, 10(10):e1004575. 2014. [PubMed]

Carter TC, Pangilinan F, Molloy AM, Fan R, Wang Y, Shane B, Gibney ER, Midttun O, Ueland PM, Cropp CD, Kim Y, Wilson AF, Bailey-Wilson JE, Brody LC, Mills JL. Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults. J Nutr Jul, 145(7):1386-1393. 2015. [PubMed]

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Last Updated: June 27, 2016