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The National Human Genome Research Institute (NHGRI) and the Wellcome Trust currently support a mouse genome sequencing project that aims to produce a robust physical map, and a high quality, finished genomic sequence of the C57BL/6J strain of Mus musculus.

This project is led by the Mouse Genome Sequencing Consortium (MGSC), a collaboration consisting of four large sequencing centers: the Broad Institute/MIT Center for Genomic Research; the Washington University Genome Sequencing Center; the Wellcome Trust Sanger Institute; The Baylor college of Medicine Human Genome Sequencing Center; and an international database, Ensembl, a joint project between the European Bioinformatics Institute and the Sanger Centre.

Project Links:
Supporting Institutions

News regarding sequencing, assembly and annotation of the mouse genome can be found in the Mouse Genome Monthly

NHGRI has also convened a group of leading mouse researchers - the Mouse Sequencing Liaison Group - to serve as a line of communication between the sequencing centers and the funding agencies, and the mouse research community.

Membership of this Mouse Sequencing Liaison Group

  • Wayne Frankel, Chair - The Jackson Laboratory
  • Rudi Balling - Gesellschaft für Biotechnologische Forschung - GBF
  • Steve Brown - MRC Mouse Genome Centre
  • Maja Bucan - University of Pennsylvania
  • Sally Camper - University of Michigan
  • David Kingsley - Stanford University
  • Janet Rossant - Mt. Sinai Hospital, Toronto
  • Eddy Rubin - Lawrence Berkeley Laboratory
  • Joseph Takahashi - Northwestern University

The Trans-NIH Mouse Initiative [nih.gov] is a source of information for the development of a wide range of genomic and genetic resources related to the laboratory mouse.

For additional information about the Trans-NIH Mouse Initiative, please contact:
Dr. Bettie Graham
E-mail: Bettie_Graham@nih.gov

Additional Resources

Sequence and Assembly
Model Organism Database
Bacterial Artificial Chromosome (BAC) End Sequencing
  • dbSNP [ncbi.nlm.nih.gov] - Database of Single Nucleotide Polymorphisms (SNPs) at NCBI
BAC Libraries
Other Related Sites

Last updated: February 15, 2014