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From Double Helix to Human Sequence - and Beyond

Natcher Auditorium
National Institutes of Health

April 14-15, 2003


Video Playlist: Deciphering Nature's Alphabet
A compilation of the 10-minute films that were produced by State of the Art, Inc. (SOTA) for NHGRI and premiered at the Scientific Symposium in 2003.

Monday, April 14, 2003

First Session: DNA at 50 years
8:30 a.m. Welcome Elias Zerhouni
National Institutes of Health
8:40 a.m. Opening Remarks Francis Collins
National Human Genome Research Institute

Aristides Patrinos
Office of Biological and Environmental Research
Department of Energy
8:50 a.m. Reflections on the 50th Anniversary James Watson
Cold Spring Harbor Laboratory

Sir Francis Crick (recorded)
Salk Institute for Biological Studies
Session Chair: Herb Boyer, Universty of California at San Francisco
9:15 a.m. YouTube video Deciphering Nature's Alphabet: How Does DNA Work? 
A Conversation
9:25 a.m. Deciphering the Genetic Code Marshall Nirenberg
National Heart, Lung and Blood Institute, NIH
9:45 a.m. Manipulating and Cloning the Double Helix Stanley Cohen
Stanford University
10:05 a.m. Break
Session Chair: Edward Rubin, Lawrence Berkeley National Laboratory and Joint Genome Institute, DOE
10:30 a.m. YouTube video Deciphering Nature's Alphabet: Manipulating DNA
A Conversation
10:40 a.m. Decoding the Information in DNA Phillip Sharp
Massachusetts Institute of Technology
11:00 a.m. YouTube video Deciphering Nature's Alphabet: Developing Genetic Tools
A Conversation
11:10 a.m. Ideological Consequences of the Human Genome Project Horace Freeland Judson
The George Washington University
11:30 a.m. Lunch
Second Session: The Human Genome Project
Session Chair: James Wyngaarden, Duke University
12:30 p.m. YouTube video Deciphering Nature's Alphabet: Imagining the Genome
A Conversation
12:40 p.m. History of the Project: Beginnings Charles DeLisi
Boston University
1987 - 1990 Bruce Alberts
National Academy of Sciences
Getting the Job Done Maynard Olson
University of Washington
Looking Beyond the Lab:
The Ethical, Legal and Social Implications Program
Eric Juengst
Case Western Reserve University
1:40 p.m. Beyond the Human Genome Eric Lander
Whitehead Institute for Biomedical Research
2:05 p.m. Break
Session Chair: Richard Gibbs, Baylor College of Medicine
2:25 p.m. Introduction to the Watson Lecture Kay Jamison
Johns Hopkins University

James Watson
Cold Spring Harbor Laboratory
2:30 p.m. Watson Lecture:
Biology in the Era of Complete Genomes
Shirley Tilghman
Princeton University
3:00 p.m. YouTube video Deciphering Nature's Alphabet: The Impact of the Human Genome Project
A Conversationhttps://www.youtube.com/watch?v=-Y0gAU9Zfzo
3:10 p.m. HGP: Beyond the Human Sequence
The Mouse Genome:
A Reflection on the Human Genome
Robert Waterston
University of Washington
New Frontiers in Comparative Genomics Eric Green
National Human Genome Research Institute
The Genome's Life Stories Patrick Brown
Stanford University
Computational Genomics: Sequence, Function and Evolution David Haussler
University of California, Santa Cruz
Human Sequence Variation David Bentley
The Wellcome Trust Sanger Institute
4:30 p.m. The Road Ahead Aristides Patrinos
Office of Biological and Environmental Research
Department of Energy
4:40 p.m. A Vision for Genomics Research Francis Collins
National Human Genome Research Institute
5:00 p.m. Adjourn

Tuesday, April 15, 2003

Third Session: Implications of Genomics for Human Disease
Session Chair: Caroline A. Kovac, IBM Life Sciences
8:30 a.m. From Genome to Successful Treatment in Leukemia Janet Rowley
University of Chicago
Genetic and Genomic Insights into Cardiovascular Disease Richard Lifton
Yale University School of Medicine
Paradigms for the Genetic Component of Diabetes Nancy Cox
University of Chicago
Gene Identification for Infectious Disease Resistence: The First 50 Years Adrian Hill
The Wellcome Trust Centre for Human Genetics
Genetics of Asthma: Role of Nonlinear Gene-Environment Interactions Fernando Martinez
University of Arizona
9:45 a.m. Questions and Discussion
10:10 a.m. Break
Fourth Session: Implications of Genomics for Human Disease
Session Chair: Michael Gottesman, National Institutes of Health
10:30 a.m. Genetics of Speech, Language and Reading Disorders Anthony Monaco
The Wellcome Trust Centre for Human Genetics
Hereditary Hearing Disorders in the Genomics Era Thomas Friedman
National Institute on Deafness and Other Communication Disorders
Impact of the Human Genome Project on Hereditary Blindness, Simple and Complex Val Sheffield
University of Iowa
Genetic Analysis Reveals Unexpected Connections Between Neurodegenerative Diseases John Hardy
National Institute on Aging
Genomic Views of Psychiatric Illness Aravinda Chakravarti
Johns Hopkins University School of Medicine
11:45 a.m. Questions and Discussion
12:10 p.m. Lunch
Fifth Session: Implications of Genomics for Healthcare
Session Chair: Raynard Kington, National Institutes of Health
1:30 p.m. Genomic Health Care Wylie Burke
University of Washington
Genes, Genomes and Drugs Peter Goodfellow
GlaxoSmithKline Pharmaceuticals
2:20 p.m. Questions and Discussion
2:40 p.m. Break
Sixth Session: Implications of Genomics for Society
Session Chair: Ellen Wright Clayton, Vanderbilt University
3:00 p.m. Race, Science and Society Harold Freeman
Columbia University and Harlem Hospital Center
Intellectual Property: A Boon or a Barrier to Genomics? Maria Freire
The Global Alliance for Tuberculosis Drug Development
The Genetic Revolution and its Impact in the Workplace Paul Miller
U.S. Equal Employment Opportunity Commission
Forensic DNA Testing and Human Identification Robert Shaler
Office of the Chief Medical Examiner New York City
4:00 p.m. Questions and Discussion
4:30 p.m. Genomics and Global Health Sir David Weatherall
University of Oxford
5:00 p.m. Adjourn

Last Reviewed: February 4, 2012

Last updated: February 04, 2012