| 8:30 a.m. | Welcome | Elias Zerhouni National Institutes of Health |
| 8:40 a.m. | Opening Remarks | Francis Collins National Human Genome Research Institute Aristides Patrinos Office of Biological and Environmental Research Department of Energy |
| 8:50 a.m. | Reflections on the 50th Anniversary | James Watson Cold Spring Harbor Laboratory Sir Francis Crick (recorded) Salk Institute for Biological Studies |
| Session Chair: Herb Boyer, Universty of California at San Francisco |
| 9:15 a.m. | Deciphering Nature's Alphabet: How Does DNA Work? A Conversation |
| 9:25 a.m. | Deciphering the Genetic Code | Marshall Nirenberg National Heart, Lung and Blood Institute, NIH |
| 9:45 a.m. | Manipulating and Cloning the Double Helix | Stanley Cohen Stanford University |
| 10:05 a.m. | Break |
| Session Chair: Edward Rubin, Lawrence Berkeley National Laboratory and Joint Genome Institute, DOE |
| 10:30 a.m. | Deciphering Nature's Alphabet: Manipulating DNA A Conversation |
| 10:40 a.m. | Decoding the Information in DNA | Phillip Sharp Massachusetts Institute of Technology |
| 11:00 a.m. | Deciphering Nature's Alphabet: Developing Genetic Tools A Conversation |
| 11:10 a.m. | Ideological Consequences of the Human Genome Project | Horace Freeland Judson The George Washington University |
| 11:30 a.m. | Lunch |
| Session Chair: James Wyngaarden, Duke University |
| 12:30 p.m. | Deciphering Nature's Alphabet: Imagining the Genome A Conversation |
| 12:40 p.m. | History of the Project: Beginnings | Charles DeLisi Boston University |
| 1987 - 1990 | Bruce Alberts National Academy of Sciences |
| Getting the Job Done | Maynard Olson University of Washington |
Looking Beyond the Lab: The Ethical, Legal and Social Implications Program | Eric Juengst Case Western Reserve University |
| 1:40 p.m. | Beyond the Human Genome | Eric Lander Whitehead Institute for Biomedical Research MIT |
| 2:05 p.m. | Break |
| Session Chair: Richard Gibbs, Baylor College of Medicine |
| 2:25 p.m. | Introduction to the Watson Lecture | Kay Jamison Johns Hopkins University James Watson Cold Spring Harbor Laboratory |
| 2:30 p.m. | Watson Lecture: Biology in the Era of Complete Genomes | Shirley Tilghman Princeton University |
| 3:00 p.m. | Deciphering Nature's Alphabet: The Impact of the Human Genome Project A Conversationhttps://www.youtube.com/watch?v=-Y0gAU9Zfzo |
| 3:10 p.m. | HGP: Beyond the Human Sequence |
The Mouse Genome: A Reflection on the Human Genome | Robert Waterston University of Washington |
| New Frontiers in Comparative Genomics | Eric Green National Human Genome Research Institute NIH |
| The Genome's Life Stories | Patrick Brown Stanford University |
| Computational Genomics: Sequence, Function and Evolution | David Haussler University of California, Santa Cruz |
| Human Sequence Variation | David Bentley The Wellcome Trust Sanger Institute |
| 4:30 p.m. | The Road Ahead | Aristides Patrinos Office of Biological and Environmental Research Department of Energy |
| 4:40 p.m. | A Vision for Genomics Research | Francis Collins National Human Genome Research Institute NIH |
| 5:00 p.m. | Adjourn |