This project is the first large-scale genetic study of African-Americans conducted almost entirely by African-American clinical investigators and scientists. The researchers are seeking national collaboration and cooperation in this study because the kinds of families required are rare. To qualify for this study, a family must be of African descent, and have at least four blood relatives who have prostate cancer, three of whom must be available for blood sampling. Eligible families should contact one of the researchers listed. Family members not living in the area may enroll at any of the seven collaborating centers. Over the next two years, the studies hope to enroll 100 families.
Howard University and NHGRI have established a center for collaborative research on genomic analysis of diseases that disproportionately affect African-Americans. The center will also lay the foundation for training African-American graduate students and postdoctoral fellows in human genome research. For the prostate cancer study, the Howard center received additional support from the NIH Office of Research on Minority Health and the National Cancer Institute (NCI) to fund collaborative recruitment centers in seven major metropolitan areas, including Chicago, IL; Washington, DC; Atlanta, GA; and Detroit, MI.
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Last Reviewed: May 20, 2010