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ELSI Sample Applications and Summary Statements

The grants listed below are examples of well-written applications that demonstrate excellent grantsmanship and that collectively represent a variety of grant mechanisms and research methodologies common to ELSI research.  Each application includes an example letter of support, provided with the permission of the letter's author.  A few samples of biosketches in the current (Summer 2016) NIH format are also included.  More information about the current NIH biosketch format is available here: Biosketch Format Pages, Instructions and Samples

Disclaimers:  All applications and summary statements have been redacted to remove personal information.  In addition, biosketches and letters of support (apart from those separately provided) have been removed to protect the privacy of co-investigators and collaborators. Please note that these applications are examples only and should not be construed as templates for preparing a grant application.  There are many different approaches to developing a successful NIH grant application. NIH grant formats or rules may have changed since these applications were prepared; therefore, applicants should always follow the application format instructions included in the funding announcement. We hope to add examples of applications submitted under other funding mechanisms in the future.  The content of these applications is copyrighted. You may use the content only for nonprofit educational purposes and only if the document remains unchanged and the PI, the grantee organization, and the NHGRI are credited. All documents are in PDF format.

Acknowledgements: We are indebted to the contributing investigators for their willingness to share their outstanding research applications and summary statements with the broader research community.

R01 Sample Applications and Summary Statements

The R01 mechanism is intended for well-integrated studies that build on preliminary data using either single or mixed methods. The Program Announcement for Ethical, Legal, and Social Implications (ELSI) of Genomic Research Regular Research Program (R01) is available here

All documents are in PDF format.

Principal Investigator Application Resources

Eric Juengst
Anticipating Personal Genomic Medicine: Impact and Implications

Summary Statement
Full Application

Gary E. Marchant
Liability in the delivery of personalized medicine: driver, impediment, or both?

Summary Statement
Full Application

David Kaufman and Amy McGuire 
Clinical Integration of Whole Genome Sequencing: A Policy Analysis

Summary Statement
Full Application
R21 Sample Applications and Summary Statements

The R21 grant mechanism is intended for projects that are primarily exploratory in nature or designed to generate pilot data in preparation for a larger study. The R21 mechanism provides a total of up to $275,000 in direct costs over two years. The Program Announcement for Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Program (R21) is available here.

Principal Investigator Application Resources

Cinnamon Bloss
Response to Testing Among Individual Consumers of DTC Personal Genomics Service

Summary Statement
Full Application

Ellen Clayton
Returning Research Results of Pediatric Genomic Research to Participants

Summary Statement
Full Application

Christian Simon, David Klein, and Helen Schartz
Interactive Multimedia and Biorepository Informed Consent

Summary Statement
Full Application
R03 Sample Applications and Summary Statements

The R03 grant mechanism is intended for small, self-contained research projects, such as those that involve single investigators. The R03 mechanism provides a total of up to $50,000 in direct costs a year for two years. The Program Announcement for Ethical, Legal, and Social Implications (ELSI) of Genomic Research Small Research Grant Program (R03) is available here.

Principal Investigator Application Resources

Maxwell Mehlman
Ethical, Legal, and Social Implications in Military Genomics

Summary Statement
Full Application

Mark Sagoff
Ecological Concepts of Human Identity in Microbiome and Metagenomic Research

Summary Statement
Full Application
Additional sample NIH grant applications may be found at:
Sample Biosketches

As of May 25, 2016, biosketches should be in the format described here: Biosketch Format Pages, Instructions and Samples

A few sample biosketches in the new format were generously contributed by the ELSI researchers listed below.

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Last Updated: July 11, 2016