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Translational and Functional Genomics Branch

The Translational and Functional Genomics Branch (TFGB) studies how genome structure and function contribute to health by exploring the genetic, epigenetic and metagenomic basis of human disorders.

Overview

TFGB researchers have developed a wide range of experimental and computational techniques to study all aspects of the genomes of humans, microorganisms that live on humans and animal models of genetic disease.

TFGB investigators catalyze technology development in genetics and computational genomics, including functional assessment, systematic mutagenesis, developmental genomics and computational analysis of both human and microbial DNA. By testing approaches and technologies in cell lines and animal models, TFGB investigators are making fundamental discoveries that will be critical to the success of human clinical trials. The long-term goal of their efforts is to successfully translate laboratory findings into improved diagnoses and therapeutics for human disorders.

Branch Staff

Julie Segre, Ph.D.
Julie Segre, Ph.D.
  • Chief & Senior Investigator
  • Translational and Functional Genomics Branch
Shawn Burgess, Ph.D.
Shawn Burgess, Ph.D.
  • Senior Investigator
  • Translational and Functional Genomics Branch
Laura Elnitski, Ph.D.
Laura Elnitski, Ph.D.
  • Senior Investigator
  • Translational and Functional Genomics Branch
Paul Liu
Paul P. Liu, M.D., Ph.D.
  • Senior Investigator
  • Translational and Functional Genomics Branch
Sean P. Conlan, Ph.D.
Sean P. Conlan, Ph.D.
  • Associate Investigator Microbial Genomics Section
  • Translational and Functional Genomics Branch

Last updated: October 21, 2016