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The technologies, inventions and discoveries of the National Human Genome Research Institute (NHGRI) are available for licensing, including tissue microarrays for rapid molecular profiling, mouse models of inherited disorders and a diverse range of genes. For a complete list of our technologies, search the NIH Office of Technology Transfer. View or list of current and past licensees of NHGRI technologies.

Patented and Patent-Pending Technologies

Assay for Predicting the Time of Onset of Niemann-Pick Disease Type C (NPC)
DHHS Reference No.: E-060-2013
U.S. Patent 9,983,200 issued on May 29, 2018
Lead Inventor: William J. Pavan, Ph.D. (NHGRI)
Office of Technology Transfer Abstract

Gene Therapy for Niemann-Pick Disease Type C (NPC)
DHHS Reference No.: E-185-2014
PCT Application PCT/US2016/026524; national phases entered in the U.S., Europe, and Canada in October 2017
Lead Inventor: Charles P. Venditti, M.D., Ph.D.
Office of Technology Transfer Abstract

New Targeted Leukemia Therapy
DHHS Reference No.: E-060-2011
U.S. Patent 9,446,048 issued September 20, 2016
German Patent 60 2012 022 372.3 issued August 31, 2016
U.K. Patent 2685985 issued August 31, 2016
Lead Inventor: P. Paul Liu, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract

Synthetic Methylmalonyl-CoA Mutase Transgene for the Treatment of Mut Class Methylmalonic Acidemia (MMA)
DHHS Reference No.: E-243-2012
U.S. Patent 9,719,080 issued August 1, 2017
U.S. Patent 9,944,918 issued April 17, 2018
U.S. Application 15/633,964, filed June 27, 2017
EP Patent 2968602 issued August 30, 2017; validated in Belgium, Switzerland, Germany, Denmark, Spain, France, U.K., Ireland, Italy, Luxembourg, Netherlands, Sweden, August 30, 2017
Lead Inventor: Charles P. Venditti, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract

Device and Method for Direct Measurement of In Vivo Oxidation
DHHS Reference No.: E-099-2009
U.S. Patent 8,293,187 Issued October 23, 2012
U.S. Patent 8,721,988 Issued May 13, 2014
Lead Inventor: Charles P. Venditti, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract

Tissue Microarrays For Rapid Molecular Profiling
DHHS Reference Nos.: E-002-1998, E-007-1999, E-272-1999, E-273-1999, and E-274-1999
U.S. Patent No. 6,699,710 issued March 2, 2004
U.S. Patent No. 6,905,823 issued June 14, 2005
Lead Inventor: Olli Kallioniemi, M.D., Ph.D.
Federal Register Description

Gene for Multiple Endocrine Neoplasia Type 1 (MEN1)
DHHS Reference No.: E-094-1997
U.S. Patent 7,358,347 issued April 15, 2008
Lead Inventors: Settara Chandrasekharappa, Ph.D. (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
News Release

Methods for Detecting Cervical Cancer
DHHS Reference No.: E-012-1997
U.S. Patent 5,919,624 issued July 6, 1999
Lead Inventor: Thomas K. Ried, M.D.

Research Materials

Mouse Models

Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular Abnormalities
DHHS Reference No.: E-243-2011
Lead Inventors: Michael R. Erdos (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)

Murine Model of Niemann-Pick Disease Type C
DHHS Reference No.: E-004-2011
Lead Inventor: William J. Pavan, Ph.D., (NHGRI)

Murine C57BL/6J Embryonic Stem Cell Lines Generated Using Serum-Free Media
DHHS Reference No.: E-038-2009/0
Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D., (NHGRI)
Office of Technology Transfer Abstract
Federal Register Description

Mouse Model of Diamond-Blackfan Anemia
DHHS Reference No.: E-294-2012
Lead Inventor: William J. Pavan, Ph.D., (NHGRI)
Federal Register Description

SAP/SH2D1A Knockout Mice: A Model for X-linked Lymphoproliferative Disease
DHHS Reference No.: E-343-2003
Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
Federal Register Description

Tec Kinase Deficient Mice
DHHS Reference Nos.: E-178-2003/0 and E-178-2003/1
Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
Federal Register Description

 

Other Research Materials

Human Melanoma Cell Lines with ERBB4 Mutations
DHHS Reference No.: E-229-2010
Lead Inventor: Yardena Samuels, Ph.D.

Human Melanoma Metastasis Cell Line with Isocitrate Dehydrogenase (IDH1) R132 Mutation
DHHS Reference No.: E-232-2010
Lead Inventor: Yardena Samuels, Ph.D.
Office of Technology Transfer Abstract

Monoclonal Antibody to the Protein NCOA6 (Also Called ASC-2 and AIB-3)
DHHS Reference No.: E-168-2005
Lead Inventor: Paul S. Meltzer, M.D., Ph.D. (NHGRI)
Federal Register Description

Addresses

Please use the following mailing address for First Class mail:

Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
6700B Rockledge Drive, MSC 6907
Bethesda, MD 20892-6907
Phone: (301) 402-2537
Fax: (301) 402-9722

Address for Deliveries (FedEx, UPS, etc.):

Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
6700B Rockledge Drive, Room 3168
Bethesda, MD 20817

  • Addresses

    Please use the following mailing address for First Class mail:

    Technology Transfer Office
    National Human Genome Research Institute (NHGRI)
    National Institutes of Health (NIH)
    6700B Rockledge Drive, MSC 6907
    Bethesda, MD 20892-6907
    Phone: (301) 402-2537
    Fax: (301) 402-9722

    Address for Deliveries (FedEx, UPS, etc.):

    Technology Transfer Office
    National Human Genome Research Institute (NHGRI)
    National Institutes of Health (NIH)
    6700B Rockledge Drive, Room 3168
    Bethesda, MD 20817

Contacts

Claire Driscoll, M.S.
Claire T. Driscoll, M.S.
  • Director
  • Technology Transfer Office
Eggerton Campbell, Ph.D.
Eggerton A. Campbell, Ph.D.
  • Senior Licensing and Patenting Manager
  • Technology Transfer Office

Last updated: June 12, 2019