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Numerous National Human Genome Research Institute (NHGRI) technologies, inventions and biological materials are available for licensing, including candidate gene therapy-based therapeutics, mouse models of genetic disorders and a diverse range of well-characterized human-derived cell lines. For a complete list of our technologies as well as a list of technologies available from all other NIH Institutes, search the NIH Office of Technology Transfer

Patented and Patent-Pending Technologies

Assay for Predicting the Time of Onset of Niemann-Pick Disease Type C (NPC)
DHHS Reference No.: E-060-2013
U.S. Patent 9,983,200 issued on May 29, 2018
Lead Inventor: William J. Pavan, Ph.D. (NHGRI)
Office of Technology Transfer Abstract

Gene Therapy for Niemann-Pick Disease Type C (NPC)
DHHS Reference No.: E-185-2014
PCT Application PCT/US2016/026524; national phases entered in the U.S., Europe, and Canada in October 2017
Lead Inventor: Charles P. Venditti, M.D., Ph.D.
Office of Technology Transfer Abstract

Synthetic Methylmalonyl-CoA Mutase Transgene for the Treatment of Mut Class Methylmalonic Acidemia (MMA)
DHHS Reference No.: E-243-2012
U.S. Patent 9,719,080 issued August 1, 2017
U.S. Patent 9,944,918 issued April 17, 2018
U.S. Application 15/633,964, filed June 27, 2017
EP Patent 2968602 issued August 30, 2017; validated in Belgium, Switzerland, Germany, Denmark, Spain, France, U.K., Ireland, Italy, Luxembourg, Netherlands, Sweden, August 30, 2017
Lead Inventor: Charles P. Venditti, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract

Device and Method for Direct Measurement of In Vivo Oxidation
DHHS Reference No.: E-099-2009
U.S. Patent 8,293,187 Issued October 23, 2012
U.S. Patent 8,721,988 Issued May 13, 2014
Lead Inventor: Charles P. Venditti, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
 

Research Materials

Mouse Models

Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular Abnormalities
DHHS Reference No.: E-243-2011
Lead Inventors: Michael R. Erdos (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)

Murine Model of Niemann-Pick Disease Type C
DHHS Reference No.: E-004-2011
Lead Inventor: William J. Pavan, Ph.D., (NHGRI)

Mouse Model of Diamond-Blackfan Anemia
DHHS Reference No.: E-294-2012
Lead Inventor: William J. Pavan, Ph.D., (NHGRI)
Federal Register Description

 

Other Research Materials

Addresses

Please use the following mailing address for First Class mail:

Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
6700B Rockledge Drive, MSC 6907
Bethesda, MD 20892-6907
Phone: (301) 402-2537
Fax: (301) 402-9722

Address for Deliveries (FedEx, UPS, etc.):

Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
6700B Rockledge Drive, Room 3168
Bethesda, MD 20817

  • Addresses

    Please use the following mailing address for First Class mail:

    Technology Transfer Office
    National Human Genome Research Institute (NHGRI)
    National Institutes of Health (NIH)
    6700B Rockledge Drive, MSC 6907
    Bethesda, MD 20892-6907
    Phone: (301) 402-2537
    Fax: (301) 402-9722

    Address for Deliveries (FedEx, UPS, etc.):

    Technology Transfer Office
    National Human Genome Research Institute (NHGRI)
    National Institutes of Health (NIH)
    6700B Rockledge Drive, Room 3168
    Bethesda, MD 20817

Contacts

Claire Driscoll, M.S.
Claire T. Driscoll, M.S., M.S.
  • Director
  • Technology Transfer Office
Anna Solowiej, Ph.D., J.D.
Anna Solowiej, Ph.D., J.D.
  • Senior Licensing and Patenting Manager
  • Technology Transfer Office
Eggerton Campbell, Ph.D.
Eggerton A. Campbell, Ph.D.
  • Senior Licensing and Patenting Manager
  • Technology Transfer Office
Sangeetha Raghavan
Sangeetha Raghavan, M.S., M.B.A.
  • Senior Licensing and Patenting Manager
  • Technology Transfer Office

Last updated: September 9, 2021