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Perspectives in Comparative Genomics and Evolution

Event Details

Live Webcast


On August 15-16, 2019, the National Human Genome Research Institute (NHGRI), the National Science Foundation (NSF) and the United States Department of Agriculture (USDA) are sponsoring a meeting Perspectives in Comparative Genomics and Evolution at the Bethesda North Marriott Hotel & Conference Center in Rockville, Maryland.

This meeting's objective is to obtain a big picture look at the current state of the field of comparative genomics with a focus on commonalities across genomic investigations into humans, model organisms (both traditional and non-traditional), agricultural species, wildlife species and microbes.

Outcomes will be threefold:

  1. Identify areas of synergy;
  2. Identify gaps in knowledge and resources that need attention and development;
  3. Recommend areas of focus for comparative genomics as a whole, and specifically to NHGRI, with relevance to understanding human health and disease.

What part of this field (if any) belongs with NHGRI and would be at the “forefront” of comparative genomics?

to

Bethesda North Marriott Hotel & Conference Center

Agenda

  • Thursday, August 15, 2019

  • 8:45 a.m. - Opening and Meeting Purpose
    Jennifer Troyer (NHGRI)
    Adele Turzillo (NIFA)
    Donal Manahan (NSF) 
  • 8:55 a.m. - Keynote: Comparative Genomics in the Coming Revolution in the Life Sciences
    Harris Lewin
  • Session One: What Is A Reference Genome and What Other Data Types Are Needed?
  • 9:35 a.m. - Generating high quality reference genomes for biology
    Erich Jarvis
  • 9:55 a.m. - Comparative epigenomic analysis of regulatory evolution in vertebrate species
    Huaijun Zhou
  • 10:15 a.m. - Plant genome dynamics: challenges and opportunities
    Robin Buell
  • 10:35 - 10:50 a.m. - Break
  • 10:50 a.m. TBD
    Carlos Bustamante
  • 11:10 a.m. Moderated Discussion
    Elinore Karlsson / Sofie Salama
  • 12:00 - 1:00 p.m. Lunch
  • Session Two: Integration and Usability of Comparative Genomics Data
  • 1:00 p.m. Plant Microbe: harmonizing diverse data sources to promote data interoperability, global-scale analysis, and reuse
    Bonnie Hurwitz
  • 1:20 p.m. Genotype-phenotype data integration across species for disease diagnosis
    Melissa Haendel
  • 1:40 p.m. Decoding the genomic landscape of de novo mutations
    Beth Dumont
  • 2:00 p.m. Moderated Discussion
    Lucia Carbone / Adam Arkin
  • 2:50 - 3:05 p.m. Break
  • Session Three: Mechanistic Function, Variation and Phenotype
  • 3:05 p.m. The search for regulatory principles governing enhancer function
    Emma Farley
  • 3:25 p.m. Comparative genomics in primates using iPSCs
    Yoav Gilad
  • 3:45 p.m. Natural Variation and Animal Models: Insights into Complexity of Pregnancy Establishment and Loss
    Tom Spencer
  • 4:10 p.m. Leveraging variation in natural systems to disentangle complex phenotypes
    Joanna Kelley
  • 4:30 p.m. Moderated Discussion
    Claudio Mello / Charles Danko
  • 5:15 p.m. Adjourn

 

  • Friday, August 16, 2019

  • 8:45 a.m. - NSF and USDA Reimbursement 101
    Eric Lyons
  • 9:00 a.m. - Keynote: How will new data and new tools shape the future of comparative genomics?
    Beth Shapiro
  • Breakout Session 1: Population Genomics
    (9:40 - 11:10 am.)
  • 9:40 a.m. Introduction
    María Ávila-Arcos / Clare Gill / Elaine Ostrander / Pam Soltis / Ted Morgan
  • 9:50 a.m. Disucssion
    All
  • Breakout Session 2: Developmental and Reproduction Genomics
    (9:40 - 11:10 am.)
  • 9:40 a.m. Introduction
    John Liu / Nipam Patel / Ollie Ryder / Tom Spencer
  • 9:50 a.m. Disucssion
    All
  • 11:10 a.m. - 11:25 a.m. Break
  • Breakout Session 3: Host/Microbial/Vector Evolution and Interaction
    (11:25 am - 12:55 p.m.)
  • 11:25 a.m. Introduction
    Hans Cheng / Elinor Karlsson / Lynn Schirml / Sue VandeWoude
  • 11:35 a.m. Discussion
    All
  • Breakout Session 4: Systems Biology
    (11:25 am - 12:55 p.m.)
  • 11:25 a.m. Introduction
    Charles Danko / Erich Jarvis / Peter Johnson / James Koltes
  • 11:35 a.m. Discussion
    All
  • 12:55 - 1:55 p.m. Lunch
  • 1:55 p.m. Report Back from Breakouts
  • 2:15 p.m. NHGRI Strategic Planning
    Eric Green
  • 3:00 p.m. Discussion: Synthesis, Synergies, and Priorities
    All
  • 4:00 p.m. Adjourn

 

Breakout Note:

The breakout sessions are designed to be an opportunity to discuss areas of overlap in our different communities (medical, agricultural, and wildlife) and think about ways that these communities might increase interactions and synergies to advance this area of science.

Organizing Committee

  • Shawn Burgess (NHGRI)
  • Charles Danko (Cornell)
  • Cyril Gay (USDA)
  • Clare Gill (Texas A&M)
  • Erich Jarvis (Rockefeller)
  • Elinor Karllson (Broad)
  • Eric Lyons (NSF)
  • Lakshmi Matukumalli (NIFA)
  • Claudio Mello (OHSU)
  • Ted Morgan (NSF)
  • Elaine Ostrander (NHGRI)
  • Lorjetta Schools (NHGRI)
  • Heidi Sofia (NHGRI)
  • Pam Soltis (University of Florida)
  • Taylorlyn Stephan (NHGRI)
  • Jennifer Troyer (NHGRI)
  • Kris Wetterstrand (NHGRI)
  • Huaijun Zhou (University of California, Davis)

Last updated: August 8, 2019