Search Results
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… Dr. Peter McGuire received his bachelor's in psychology from Villanova … for Inherited Metabolic Diseases at Mount Sinai. Dr. McGuire is board certified in Pediatrics, Clinical Genetics and Biochemical Genetics. In 2010, Dr. McGuire moved to the National Institutes of Health (NIH) to …
News Release
A new study highlights how genomic mutations that cause mitochondrial disease may also compromise affected people's immune response.
… protective immunity after vaccination, according to Peter McGuire, M.D., senior author and investigator at the National … During T Cell Activation and Differentiation [cell.com] Peter McGuire, M.D. Medical Genomics and Metabolic Genetics … Mitochondrial disease, human immune response, Peter McGuire M.D. …
News Release
The Physician-Scientist Development Program helps physicians develop research programs dedicated to the disorders they specialize in.
… an eager medical student in his first pediatrics rotation, Peter McGuire treated a child suffering from glutaric aciduria type … a rare genetic disease with no known cure. Today, Dr. McGuire is one of the world's leading experts in the disease, … unwell, and infections push them over the edge," said Dr. McGuire referring to a phenomenon known as metabolic …
FAQ
Addressing the COVID-19 pandemic and what it means to the pediatric mitochondrial disease community.
… Peter McGuire is an investigator and head of the Metabolism, … metabolism, organ dysfunction, tissue death, MINI Section, Peter McGuire …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… they can worsen the progression of their disorder,” said Peter McGuire, M.B.B.Ch. , NHGRI investigator, head of the … to survive by producing the microRNA to cope,” said Dr. McGuire. “But the B cells are too fragile due to their …
Clinical Research
The Metabolism, Infection and Immunity (MINI) Section aims to define the relationship between infection, immunity and clinical decline in individuals with mitochondrial disease.
… the first critical step to improving their wellbeing.” - Peter McGuire, M.D., Principal Investigator …
Staff
Dr. Gordon-Lipkin is a researcher and child neurologist with expertise in neurodevelopmental disabilities in the Metabolism, Infection and Immunity (MINI) Section.
… and multiple sclerosis. Her current work with Dr. Peter McGuire in the MINI Section at NHGRI focuses on immune … EM , Banerjee P, Thompson E, Kruk S, Franco JLM, McGuire PJ. Epitope-level profiling in children with … Rep . 2022 Mar;30:100837. Sturrock BRH, Macnamara EF, McGuire P, Kruk S, Yang I, Murphy J, Tifft CJ, Gordon-Lipkin …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… The new FAQ page, developed by NHGRI intramural researcher Peter McGuire, M.D. , provides details about pediatric … Videos Pediatric mitochondrial disease and COVID-19 — Peter McGuire Fueling the next genomic revolution: Maximizing the …
Staff
Dr. Lucia Hindorff is the Lead Extramural Training Program Director in the Training, Diversity, and Health Equity Office at the National Human Genome Research Institute.
… Koenig BA, Krantz ID, Manolio TA, McCullough L, McEwen J, McGuire A, Muzny D, Myers RM, Nickerson DA, Ou J, Parsons DW, …
Clinical Research
A Longitudinal Natural History Study of Children with Mitochondrial Disease (at the NIH Clinical Center).
… is the first critical step to improving their well-being. Peter McGuire, M.D. Principal Investigator …