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Educational Resources
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
… Frameshift Mutation … A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide … Genetic Mutation, Base Pairs, DNA Sequence … A frameshift mutation in a gene refers to the insertion or deletion of … of 20 different amino acids used to build a protein. If a mutation disrupts this normal reading frame, then the entire …
Educational Resources
A nonsense mutation is the substitution of a single base pair that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid.
… Nonsense Mutation … A nonsense mutation is the substitution of a single base pair that leads … Nonsense Mutation, Missense Mutation, Base Pair, Genetic Code, Genetic Mutation … A nonsense mutation occurs in DNA when a sequence change gives rise to a … A nonsense mutation is the substitution of a single base pair that leads …
Educational Resources
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
… Mutation … A mutation is a change in a DNA sequence. Mutations can result … Mutation, DNA Sequence, Germ Line, Gene … A mutation is a change in the DNA sequence of an organism. … A mutation is a change in a DNA sequence. Mutations can result …
Educational Resources
A point mutation is when a single base pair is altered.
… Point Mutation … A point mutation is when a single base pair is altered. … Amino Acids, Base Pair, Codon, Missense Mutation, Nonsense Mutation, Protein, Stop Codon, Mutation … A point mutation occurs in a genome when a single base pair is added, … A point mutation is when a single base pair is altered. …
Educational Resources
A missense mutation is when the change of a single base pair causes the substitution of a different amino acid in the resulting protein.
… Missense Mutation … A missense mutation is when the change of a single base pair causes the … Missense Mutation, DNA Mutation, DNA Sequence … A missense mutation is a DNA change that results in different amino … A missense mutation is when the change of a single base pair causes the …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… that these cells are prone to increased numbers of genetic mutations. A new study by scientists at the National … were reprogrammed and in cells that were subcloned. M ost genetic variants detected in the iPSCs and subclones were rare genetic variants inherited from the parent skin cells. This …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… in the TAF1 gene. They've also demonstrated that the mutation profiles of CCEC tumors are sometimes similar to … cells from patients with CCEC. Their goal was to identify genetic mutations in CCEC tumor cells that are absent from … 47 CCEC patients. Their results defined the frequency of mutation of the genes previously implicated in CCEC ( TP53 , …
Educational Resources
Deletion is a type of mutation involving the loss of genetic material.
… Deletion is a type of mutation involving the loss of genetic material. … Genetic Mutation, Base Pair, DNA, Chromosome … A deletion, as related to genomics, is a type of mutation that involves the loss of one or more nucleotides … Deletion is a type of mutation involving the loss of genetic material. …
News Release
Researchers sequence the genomes of healthy participants, then analyze the data to find presumed, mutations that might lead to a genetic condition.
… genomics research on its head. Instead of trying to find a mutation in the genomic sequence of a person with a genetic disease, they sequenced the genomes of healthy … presumed, mutations that would almost certainly lead to a genetic condition. … that 34 had the specific condition linked to their genetic mutation. These findings indicate that 3 percent or …
Genetic Disorders
Fragile X syndrome is an inherited intellectual disability caused by a mutation in the FMR1 gene.
… is an inherited intellectual disability caused by a mutation in the FMR1 gene. … cases of fragile X syndrome are caused by an alteration (mutation) in the FMR1 gene where a DNA segment, known as the … A boy who has the full FMR1 mutation has fragile X syndrome and will have moderate …