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News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… any adult cell to its earliest stage of development (a pluripotent stem cell) and change it into different types of cells in the body. … Called induced pluripotent stem cells (iPSCs), this technique opens … mutations. A new study by scientists at the National Human Genome Research Institute (NHGRI), part of the National …
Educational Resources
A stem cell is a cell with the potential to form many of the different cell types found in the body.
… Stem Cell … A stem cell is a cell with the potential to form many of the … A stem cell is a cell with the potential to form many of the different cell types found in the body. When stem cells divide, they can form more stem cells or other cells …
Staff
Dr. Manfred Boehm is a an adjunct investigator for the Office of the Clinical Director at NHGRI.
… boards of Trends in Cardiovascular Medicine , ISRN Stem Cells , Atherosclerosis , and Journal of Molecular Medicine . … acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in … Manfred Boehm, human vascular diseases, precision medicine, human induced …
Educational Resources
A somatic cell is any cell of the body except sperm and egg cells.
… Somatic Cells … A somatic cell is any cell of the body except sperm and egg cells. … Somatic cells are the cells in the body other than sperm and egg cells (which are called germ cells). In humans, somatic cells … A somatic cell is any cell of the body except sperm and egg cells. …
News Release
In a study published in the journal Science, collaborators at NHGRI, the National University of Ireland, Galway, and the Whitney Laboratory for Marine Bioscience at the University of Florida, Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ cells in a cycle that can repeat endlessly.
… research of Hydractinia  could provide clues to human reproductive conditions. … ability could provide insight into the development of human reproductive system and the formation of … reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ …
Educational Resources
A cell cycle is a series of events that takes place in a cell as it grows and divides.
… mitosis, and completes its division. The resulting cells, known as daughter cells, each enter their own interphase and begin a new round …
Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
… from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) are smooth and …   Researchers used bioengineering to create mice with a human gene that produces the defective hemoglobin causing … "corrected" by the addition of the anti-sickling human beta-hemoglobin gene. The corrected marrow was then …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… its make-up is different among cell types, even among cells that are similar. Investigators from two National Human Genome Research Institute (NHGRI)-funded programs, the … what to do - among three types of cells: mouse embryonic stem (ES) cells, embryonic fibroblasts and hematopoietic …
Educational Resources
The cell membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside environment.
… membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside … Plasma Membrane, Proteins, Glycoproteins, Lipid Bilayer, Cells … membrane, also called the plasma membrane, is found in all cells and separates the interior of the cell from the outside …
Educational Resources
A cell is the basic building block of living things.
… A cell is the basic building block of living things. All cells can be sorted into one of two groups: eukaryotes and … not. Plants and animals are made of numerous eukaryotic cells, while many microbes, such as bacteria, consist of single cells. An adult human body is estimated to contain between 10 and 100 …