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Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number of new … about the biology and development of a rare form of kidney cancer. … cancer, and shed light on the role of mitochondria and metabolic pathways in cancer. The results also support the …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung … common subtype of lung cancer. Knowledge of these genomic changes may expand the number of possible therapeutic targets …
Staff
Christine Chang is a program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
… Christine Chang is a program officer in the Division of Genomic Medicine, joining the National Human Genome Research Institute in 2014. She manages a portfolio of grants in genomic … Analyst program. Prior to joining NHGRI, Ms. Chang was a Cancer Research Training Fellow at the National Cancer …
Genetic Disorders
Inborn errors of metabolism are disorders that cause a block in a metabolic pathway leading to clinically significant consequences.
… is a sequence of chemical reactions that take place in cells in the body. These reactions are responsible for the … (IEM) are a group of disorders that causes a block in a metabolic pathway leading to clinically significant … they also have the disorder. We recommend talking to your metabolic specialist and/or genetic counselor to determine …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … A cancer-susceptibility gene is a gene that, when changed (or … cancer. Individuals who have inherited mutations in certain cancer-susceptibility genes have a lifetime risk …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… Breast cancer is the second most common cancer in women after skin cancer. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and … a common disease. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and …
CRGGH is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch.
… and Global Health (CRGGH) is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics … Director, Dan Kastner, this reorganization was conducted, in part, to facilitate new "scientific synergies." These … MCIDGB Branch Chief, a major scientific leadership role in the Intramural Research Program. …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United States. An estimated 40 to 50 percent of … Skin cancer is the most common type of cancer in the United … skin cancer. It occurs when melanocytes, the pigment cells in the lower part of the epidermis, become malignant, meaning …
News Release
The TCGA network describes uterine and bile duct cancer.
… The Cancer Genome Atlas (TCGA), a program co-funded by the National Cancer Institute and NHGRI, has greatly improved our … - outlining the molecular similarities between different cancer patients and cancer types, as well as documenting what … total from 33 cancer types, catalogs all the key genomic changes - the modifications in DNA, RNA and proteins that …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
… Cancer … Cancer is a group of diseases characterized by uncontrolled … Cancer, Cell Division, Mutation, DNA Error, Metastasis, … Cancer is a disease in which some of the body’s cells grow … Cancer is a group of diseases characterized by uncontrolled …