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Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… 1900s. More recently, a new genome editing tool called CRISPR, invented in 2009, has made it easier than ever to edit DNA. CRISPR is simpler, faster, cheaper, and more accurate than … Many scientists who perform genome editing now use CRISPR. … delete different genes in zebrafish one at a time using CRISPR to see how the deletion impacts the fish. The Burgess …
News Release
NIH will hold a Reddit "Ask Me Anything" with members of its NHGRI Ethical, Legal and Social Implications Research Program.
… diseases? What kinds of questions do new technologies like CRISPR-Cas9 raise? The Ethical, Legal and Social Implications … Lawrence Brody Ph.D., bioethics and genomic research, CRISPR-Cas9
News Release
Researchers have identified genomic mutations for Carey-Fineman-Ziter syndrome, a congenital myopathy with facial weakness, a cleft palate and scoliosis.
… this gene a promising candidate for further studies. Using CRISPR-Cas9 technology , a tool for editing DNA at precise … Syndrome Research Consortium, Moebius syndrome Foundation, CRISPR-Cas9 technology …
Media Advisory
NHGRI hosts a Reddit AMA with Jennifer Doudna, Ph.D., and her research group.
… Media Advisory CRISPR-Cas9 is a customizable tool that lets scientists cut and … center will focus on refining technologies, such as the CRISPR-Cas9 gene-editing system, that alter, detect, and record the … NIH to host a Reddit "Ask Me Anything" with CRISPR scientist, Dr. Jennifer Doudna …
Outreach
The USA Science and Engineering Festival is an opportunity to take part in hands-on genetics and genomics activities.
… members and friends. Go to the Genetic Trait Tree .   The CRISPR Corner Are you familiar with the term “gene editing”? … the science behind one specific gene editing tool called CRISPR-Cas9. After learning the basics, participants will be asked …
Staff
Dr. Raman Sood is an associate investigator in the Translational and Functional Genomics Branch and director of the Zebrafish Core at the National Human Genome Research Institute. ​
… mutagenesis using genome editing nucleases, particularly CRISPR/Cas9 to generate single or multiple gene knockout mutants in … generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes . DNA Repair 107: 103173. … associated with holoprosencephaly in humans using a CRISPR/Cas9 zebrafish model . Human Mutation , 41 (12): 2155-2166. …
Professional Development Programs
The Short Course in Genomics offers educators a chance to hear lectures and receive teaching resources from leading researchers, clinicians and staff.
… Branch, illustrates how to assemble a paper-based CRISPR-Cas9 kit for a hands-on CRISPR technology demonstration. Model is adapted from …
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… them fluorescent. But in 2012, a  new technique called CRISPR  was developed and has revolutionized genome editing. The scientists who developed CRISPR recognized that they could borrow tools from the  … scissors" for surgically editing any DNA in any organism. CRISPR has made genome editing much simpler, faster, cheaper, …
News Release
In 1982, John Carey, M.D., and his colleagues named the rare disease, Carey-Fineman-Ziter syndrome. Now, researchers have identified the genomic mutations.
… d/areas-focus/project-spotlight/questions-and-answers-about-crispr" … d/areas-focus/project-spotlight/questions-and-answers-about-crispr">CRISPR-Cas9</a> might be used to edit the genomic mutations in …
News Release
Researchers and clinicians are sequencing human genomes faster than ever, so considering the societal implications of genomic data is even crucial.
… in learning more about how gene editing technologies, like CRISPR-Cas9, could enhance the human condition. From FlyInSpace When … of people's minds given all the attention and promise of CRISPR gene editing technology. It's important to keep in …