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The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… Each news cycle brings reminders about the importance of science and its critical role in society, and NHGRI … remains more committed than ever to facilitating the use of genomics for addressing all threats to human health – … historical milestone for genomics: the 30th anniversary of the launch of the Human Genome Project in October 2020. To …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… , scientists have set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works. A better understanding of chromatin will yield important insights into the genome's … Genome Research Institute (NHGRI)-funded programs, the Encyclopedia of DNA Elements (ENCODE) project and the Centers …
Staff
Dr. Mike Pazin is a program director in the Division of Genome Sciences at the National Human Genome Research Institute.
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… NHGRI's Extramural Research Program in 2011. Mike is part of the NHGRI team overseeing the IGVF Consortium , developing … a framework for systematically understanding the effects of genomic variation on genome function and how these effects … He has worked on the NHGRI Data Access Committee, the ENCODE project , Common Fund Epigenomics modENCODE , the …
Event
Joint workshop featuring overviews of Roadmap Epigenomics and ENCODE resources that are freely available for use by the research community.
… The Encyclopedia of DNA Elements (ENCODE) and the Common Fund-supported Roadmap … Society of Toxicology Annual Meeting … A Toxicology User's Guide to the Roadmap Epigenomics and ENCODE Data Resources … Joint workshop featuring overviews of Roadmap Epigenomics and ENCODE resources that are freely …
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… DNA Sequencing … DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule. … Adenine, Cytosine, Guanine, Thymine, ACGT, DNA, DNA Sequencing … laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. The sequence of …
Educational Resources
DNA replication is the process by which a molecule of DNA is duplicated.
… DNA Replication … DNA replication is the process by which a molecule of DNA is duplicated. … DNA, Cell Division, Cell Biology … DNA replication is the process by which the genome’s DNA is copied in cells. Before a cell divides, it must first … DNA replication is the process by which a molecule of DNA is duplicated. …
15 Ways Genomics Influences Our World
We are learning how our genomes serve as blueprints for life.
… Did you know that just knowing the genome sequence of an organism only reveals part of the story - and that it is also important to determine how … build and operate itself accordingly? Less than 2 percent of the human genome corresponds to "genes," but we know other …
Event
On Sept. 30 - Oct. 2, 2020, the National Human Genome Research Institute (NHGRI) sponsored the ENCODE 2020: Research Applications and Users Meeting.
… Human Genome Research Institute (NHGRI) sponsored the ENCODE 2020: Research Applications and Users Meeting. The goal of the meeting was to help researchers leverage ENCODE’s 15,000+ freely available genomic datasets to … ENCODE 2020: Research Applications and Users Meeting …
Staff
Dr. Elise Feingold was a scientific program manager in NHGRI's Division of Genome Sciences.
… for the prioritization, development and implementation of new initiatives both within the Division of Genome … 2013. From 2003-2019, Dr. Feingold initiated and led the Encyclopedia of DNA Elements (ENCODE) project, which aimed to generate a … W, Ryba T et al. (Mouse ENCODE Consortium) A comparative encyclopedia of DNA elements in the mouse genome . Nature , …
Fact Sheets
A DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes.
… The DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes. … that a mutation - or alteration - in a particular gene's DNA may contribute to a certain disease. However, it can be … in the genes BRCA1 and BRCA2 cause as many as 60 percent of all cases of hereditary breast and ovarian cancers. But …