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News Release
NIH researchers and collaborators have found that that sickle cell trait is prevalent among diverse human populations.
… Study finds that sickle cell trait is prevalent among diverse human populations. … and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait , increases … Genetic carriers for sickle cell disease have higher risks of blood clots across …
Health FAQ
Discuss these questions with your doctor or health care provider.
… Education Project welcomes your feedback about the sickle cell disease gene therapy resources. Please email your comments or … criteria across all therapies, including your age, your sickle disease genotype, other treatments you are taking, your … make a plan for the treatments you are taking for your sickle cell disease. For example, if you are taking …
News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
… 2.5 to 3 million people have a gene variant associated sickle cell trait (SCT) and most never have related health … may increase risk for some individuals." Hematologists and sickle cell experts evaluated the association of SCT with 24 health … Systematic review study supports that sickle cell trait increases risk for some health conditions …
Fact Sheet
Understanding gene therapy for sickle cell disease
… Sickle cell disease is the most common inherited blood disorder in the … there are only a handful of options to manage or treat sickle cell disease.  Now, researchers are developing new and … Education Project welcomes your feedback about the sickle cell disease gene therapy resources. Please email your …
Fact Sheet
Sickle cell disease resources for healthcare providers
… Education Project welcomes your feedback about the sickle cell disease gene therapy resources. Please email your comments or … Management of SCD: Expert Panel Review, 2014 CDC Sickle Cell Info for Healthcare Providers  American College of … CURE Sickle Cell: Resource Library ASH Shared Decision Making …
News Release
NHGRI researchers asked patients, parents and physicians in the sickle cell disease community (SCD) what they wanted and needed to know about genome editing to make informed decisions about participating in genome-editing clinical trials.
… of Health, asked patients, parents and physicians in the sickle cell disease community what they wanted and needed to know about … researchers asked patients, parents and physicians in the sickle cell disease community (SCD) what they wanted and needed to … sickle cell disease, informed consent, genome editing, …
Educational Resources
A somatic cell is any cell of the body except sperm and egg cells.
… A somatic cell is any cell of the body except sperm and egg cells. … Cell, Chromosome, Diploid, Mutation, Germ Line … A somatic cell is any cell of the body except sperm and egg cells. …
Educational Resources
A cell cycle is a series of events that takes place in a cell as it grows and divides.
… Cell Cycle … A cell cycle is a series of events that takes place in a cell as it grows and divides. … Cell Division, Basic Biology, DNA Synthesis … A cell cycle is a series of events that takes place in a cell as it grows and divides. A cell spends most of its time …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… long-lasting antibodies that will defend the body against disease for years. Now, a team headed by scientists at the … that a transcription factor known as TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream. TCF1 doesn't …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… these components differ and other treatment options for sickle cell disease, such as bone marrow transplant.  Each of these … target the blood stem cells to reduce your symptoms of sickle cell disease.  Gene therapies use your own stem cells, while … with new stem cells that have genes that do not code for sickle cell disease. These new stem cells are usually from …